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A5LN20 (A5LN20_STRPN) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phospho-2-dehydro-3-deoxyheptonate aldolase PIRNR PIRNR001361
EC=2.5.1.54 PIRNR PIRNR001361
Alternative name(s):
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase PIRNR PIRNR001361
DAHP synthase PIRNR PIRNR001361
Phospho-2-keto-3-deoxyheptonate aldolase PIRNR PIRNR001361
Gene names
ORF Names:CGSSp6BS73_07634 EMBL EDK76181.1
OrganismStreptococcus pneumoniae SP6-BS73 EMBL EDK76181.1
Taxonomic identifier406557 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length343 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) By similarity. PIRNR PIRNR001361

Catalytic activity

Phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate. PIRNR PIRNR001361

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7. PIRNR PIRNR001361

Sequence similarities

Belongs to the class-I DAHP synthase family. PIRNR PIRNR001361

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Sequences

Sequence LengthMass (Da)Tools
A5LN20 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 573CC7A247AD71ED

FASTA34338,753
        10         20         30         40         50         60 
MAFIEKGQEI DMEVIKAETQ LSAEALRLKE SRDRELADII SGEDDRILLV IGPCSSDNEE 

        70         80         90        100        110        120 
AVLEYARRLS ALQKKVADKI FMVMRVYTAK PRTNGDGYKG LVHQPDTSKA PSLINGLQAV 

       130        140        150        160        170        180 
RQLHYRVITE TGLTTADEML YPSNLILVDD LVSYHAVGAR SVEDQEHRFV ASGIDAPVGM 

       190        200        210        220        230        240 
KNPTSGNLGV MFNAIYAAQN KQTFLYHGQE VETSGNPLAH VILRGAVNEY GNYMPNYYYE 

       250        260        270        280        290        300 
NLLQAIERYE TMGLENPFIL IDTNHDNSGK QYMEQIRIVR QTLQNRDWNE KIKKTVRGFM 

       310        320        330        340 
IESYLADGRQ NQPEIFGCSI TDPCLGWENT EALVEEIYVT LTK

« Hide

References

[1]"Comparative genomic analyses of seventeen Streptococcus pneumoniae strains: insights into the pneumococcal supragenome."
Hiller N.L., Janto B., Hogg J.S., Boissy R., Yu S., Powell E., Keefe R., Ehrlich N.E., Shen K., Hayes J., Barbadora K., Klimke W., Dernovoy D., Tatusova T., Parkhill J., Bentley S.D., Post J.C., Ehrlich G.D., Hu F.Z.
J. Bacteriol. 189:8186-8195(2007) [PubMed: 17675389] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: SP6-BS73 EMBL EDK76181.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		ABAA01000008 Genomic DNA. Translation: EDK76181.1.

3D structure databases

ProteinModelPortalA5LN20.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

PATRIC29707116. VBIStrPne92647_1471.

Phylogenomic databases

OMAMDNSFKL.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR006218. DAHP1/KDSA.
IPR006219. DHAP_synth_1.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHERPTHR21225. AroFGH. 1 hit.
PfamPF00793. DAHP_synth_1. 1 hit.
[Graphical view]
PIRSFPIRSF001361. DAHP_synthase. 1 hit.
TIGRFAMsTIGR00034. AroFGH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA5LN20_STRPN
AccessionPrimary (citable) accession number: A5LN20
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info