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A5KI93 (A5KI93_CAMJE) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase HAMAP MF_00387
Short name=UDP-N-acetylglucosamine acyltransferase HAMAP MF_00387
EC=2.3.1.129 HAMAP MF_00387
Gene names
Name:lpxA HAMAP MF_00387
ORF Names:Cj8486_0257 EMBL EDK21496.1
OrganismCampylobacter jejuni subsp. jejuni CG8486 EMBL EDK21496.1
Taxonomic identifier398000 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length263 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. HAMAP MF_00387 SAAS SAAS010137

Catalytic activity

(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetylglucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. HAMAP MF_00387 SAAS SAAS010137

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. HAMAP MF_00387 SAAS SAAS010137

Subunit structure

Homotrimer By similarity. HAMAP MF_00387 SAAS SAAS010137

Subcellular location

Cytoplasm By similarity HAMAP MF_00387.

Sequence similarities

Belongs to the transferase hexapeptide repeat family. LpxA subfamily. HAMAP MF_00387

Sequences

Sequence LengthMass (Da)Tools
A5KI93 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: 7235017BC7CBF2B7

FASTA26328,625
        10         20         30         40         50         60 
MKKIHPSAVI EEGAQLGDDV VVEAYAYVSK DAKIGNNVVI KQGARILSDT TIGDHSRVFS 

        70         80         90        100        110        120 
YAIVGDIPQD ISYKEEQKSG VVIGKNATIR EFATINSGTA KGDGFTRIGD NAFIMAYCHI 

       130        140        150        160        170        180 
AHDCLLGNNI ILANNATLAG HVELGDFTVV GGLTPIHQFV KVGEGCMIAG ASALSQDIVP 

       190        200        210        220        230        240 
FCLAEGNRAS IRSLNLVGTR RRFDKDEVDR LSRAFKTLFR QGDLKENAKN LLENQESENV 

       250        260 
KKMCHFILET KRGIPVYRGK NNA

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References

[1]"Genome sequence of a clinical isolate of Campylobacter jejuni from Thailand."
Poly F., Read T., Tribble D.R., Baqar S., Lorenzo M., Guerry P.
Infect. Immun. 75:3425-3433(2007) [PubMed: 17438034] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: CG8486 EMBL EDK21496.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AASY01000013 Genomic DNA. Translation: EDK21496.1.

3D structure databases

ProteinModelPortalA5KI93.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

PATRIC27759548. VBICamJej15397_1807.

Family and domain databases

HAMAPMF_00387. LpxA.
[Tree]
InterProIPR001451. Hexapep_transf.
IPR018357. Hexapep_transf_CS.
IPR010137. Lipid_A_lpxA.
IPR011004. Trimer_LpxA-like.
[Graphical view]
PfamPF00132. Hexapep. 3 hits.
[Graphical view]
PIRSFPIRSF000456. UDP-GlcNAc_acltr. 1 hit.
SUPFAMSSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMsTIGR01852. Lipid_A_lpxA. 1 hit.
PROSITEPS00101. HEXAPEP_TRANSFERASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5KI93_CAMJE
AccessionPrimary (citable) accession number: A5KI93
Entry history
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info