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Protein

Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

Gene

PVX_001900

Organism
Plasmodium vivax (strain Salvador I)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Cofactori

(R)-lipoateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.-UniRule annotation)
Gene namesi
ORF Names:PVX_001900Imported
OrganismiPlasmodium vivax (strain Salvador I)Imported
Taxonomic identifieri126793 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Plasmodium)
Proteomesi
  • UP000008333 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiPlasmoDB:PVX_001900

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_500268531318 – 613Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexSequence analysisAdd BLAST596

Interactioni

Protein-protein interaction databases

STRINGi5855.PVX_001900

Structurei

3D structure databases

ProteinModelPortaliA5KCF0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini52 – 127Lipoyl-bindingInterPro annotationAdd BLAST76
Domaini185 – 260Lipoyl-bindingInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation

Keywords - Domaini

LipoylUniRule annotation, SignalSequence analysis

Phylogenomic databases

HOGENOMiHOG000284461
InParanoidiA5KCF0
KOiK00627
OMAiRAMAQNM

Family and domain databases

Gene3Di3.30.559.10, 1 hit
InterProiView protein in InterPro
IPR003016 2-oxoA_DH_lipoyl-BS
IPR001078 2-oxoacid_DH_actylTfrase
IPR000089 Biotin_lipoyl
IPR023213 CAT-like_dom_sf
IPR011053 Single_hybrid_motif
PfamiView protein in Pfam
PF00198 2-oxoacid_dh, 1 hit
PF00364 Biotin_lipoyl, 2 hits
SUPFAMiSSF51230 SSF51230, 2 hits
PROSITEiView protein in PROSITE
PS50968 BIOTINYL_LIPOYL, 2 hits
PS00189 LIPOYL, 2 hits

Sequencei

Sequence statusi: Complete.

A5KCF0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLLWLPFFL LLRTSTCISL PNKHGFITTL NHAWAKSPHN KMKNRRGVIF
60 70 80 90 100
SQIEIKMPAL SSTMTSGKIV KWNKDVGEYV NLGDIIMTVE SDKADMDVEA
110 120 130 140 150
FDEGFLRVKH MGDGSEAKVG DTLGILTTEE DEEIEAPSDD FPAGGTTPQG
160 170 180 190 200
GITSHGDITP EGETTPQGDS PHAQAPQPAQ QQTGERKIFL PFVSTKRNRA
210 220 230 240 250
RISKWTRKEN DRIEKDEVLF HVEDDKSTIE VESPCNGVVK KIFIEEGQFA
260 270 280 290 300
DFEKPVAIIS PRKAEDPPQG EQTEDVQPVN EENVVRHYRE ALSGTREGEL
310 320 330 340 350
LLQNMSASDK RTMEERLLLN YDKYTPLSRD FFSSRDDGTP GKGSTGQKRD
360 370 380 390 400
TVMEQNKLTP ADIKGTKVPG RITYEDVISH LERTKGETPA KAKIIELTNV
410 420 430 440 450
QKAIKNNMMR TLSIPVFRIT HFIKTNALLK LYEQVKDKIN MTVLLCKCVA
460 470 480 490 500
KVLLKHPIIY STFIDEGEGK ILFNEDVHIG NALGLKNSLL TPVLKRVNKA
510 520 530 540 550
DIYTLAGEWK KLVEKGKQGL LTAGEMSGSN FYISNLGMLN TYQFDATLPP
560 570 580 590 600
NVSCILSVGT NIARVENLED LKIQRGMMMT LTCDHRHIYG SHAAAFMSDL
610
AAFVERDIMQ VFL
Length:613
Mass (Da):68,601
Last modified:July 10, 2007 - v1
Checksum:i7CA2A8CF9D7BB140
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAKM01000021 Genomic DNA Translation: EDL43014.1
RefSeqiXP_001612741.1, XM_001612691.1

Genome annotation databases

EnsemblProtistsiEDL43014; EDL43014; PVX_001900
GeneIDi5471988
KEGGipvx:PVX_001900

Similar proteinsi

Entry informationi

Entry nameiA5KCF0_PLAVS
AccessioniPrimary (citable) accession number: A5KCF0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: March 28, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health