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Protein

Hexokinase

Gene

PVX_114315

Organism
Plasmodium vivax (strain Salvador I)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
ORF Names:PVX_114315Imported
OrganismiPlasmodium vivax (strain Salvador I)Imported
Taxonomic identifieri126793 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Plasmodium)
ProteomesiUP000008333 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiPlasmoDB:PVX_114315.

Interactioni

Protein-protein interaction databases

STRINGi5855.PVX_114315.

Structurei

3D structure databases

ProteinModelPortaliA5K274.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000162670.
InParanoidiA5K274.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5K274-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYYNLEKDD TVYYKLDTIK CDIPINEELQ ARINKHVNQL RITYSTLEEF
60 70 80 90 100
VDNFVYELKK GLEAHRRHPN LWIPHECSFK MLDSCIADIP TGQEKGTYYA
110 120 130 140 150
IDFGGTNFRA VRASLDGNGK IKRDQETYSL KFTGTFSHEK GLLDKHATAS
160 170 180 190 200
QLFDHFAERI KYIMGEFKDL DNPEGKNVGF TFSFPCTSPS INCSILIDWT
210 220 230 240 250
KGFETGRATN DPVEGRDVCK LMNDAFVRSE VPAKVCCVVN DAVGTLMSCA
260 270 280 290 300
YQKGKTTPPC YIGIILGTGS NGCYYEPEWK KYKYSGKIIN IELGNFDKDL
310 320 330 340 350
PLSPIDLVMD WHSANRSRQL FEKMISGAYL GEIVRRFMVN VLQSASSEKM
360 370 380 390 400
WKSDSFNSEL GSVVLNDTSP NFEESRKVAK DAWDMDFTDE QIYALRKICE
410 420 430 440 450
SVYNRSAALA AAAIAAIAKR IKIIEHSKFS CGVDGSLFVK NAWYCKRLQE
460 470 480 490
HLKVILADKA ENLIIIPADD GSGKGAAITA AVVSQSSSIK QLP
Length:493
Mass (Da):55,375
Last modified:July 10, 2007 - v1
Checksum:i104B7D50068C8A4C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAKM01000003 Genomic DNA. Translation: EDL46524.1.
RefSeqiXP_001616251.1. XM_001616201.1.

Genome annotation databases

GeneIDi5475550.
KEGGipvx:PVX_114315.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAKM01000003 Genomic DNA. Translation: EDL46524.1.
RefSeqiXP_001616251.1. XM_001616201.1.

3D structure databases

ProteinModelPortaliA5K274.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5855.PVX_114315.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5475550.
KEGGipvx:PVX_114315.

Organism-specific databases

EuPathDBiPlasmoDB:PVX_114315.

Phylogenomic databases

HOGENOMiHOG000162670.
InParanoidiA5K274.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Salvador IImported.

Entry informationi

Entry nameiA5K274_PLAVS
AccessioniPrimary (citable) accession number: A5K274
Entry historyi
Integrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: June 24, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.