Hydrolase, putative - Plasmodium vivax (strain Salvador I)

Preferred order of sections

Names and origin

Protein names

Submitted name:
Hydrolase, putative EMBL EDL47624.1

Gene names

ORF Names:

PVX_123945 EMBL EDL47624.1

Organism

Plasmodium vivax (strain Salvador I)

Taxonomic identifier

126793 [NCBI]

Taxonomic lineage

Eukaryota › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodium › Plasmodium (Plasmodium)

Protein attributes

Sequence length	293 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Ontologies

Keywords
Ligand	Calcium PDB 2B30 Metal-binding PDB 2B30
Molecular function	Hydrolase EMBL EDL47624.1
Technical term	3D-structure PDB 2B30 Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	hydrolase activity Inferred from electronic annotation. Source: UniProtKB-KW metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Sites

Metal binding

25

1

Calcium PDB 2B30

Metal binding

27

1

Calcium; via carbonyl oxygen PDB 2B30

Metal binding

240

1

Calcium PDB 2B30

Sequences

Sequence

Length

Mass (Da)

Tools

A5K063 [UniParc].

Last modified July 10, 2007. Version 1.
Checksum: F17163ABC93C0A02
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FASTA

293

33,158

        10         20         30         40         50         60 
MADQNPDLKV EEALKGADIK LLLIDFDGTL FVDKDIKVPS ENIDAIKEAI EKGYMVSICT 

        70         80         90        100        110        120 
GRSKVGILSA FGEENLKKMN FYGMPGVYIN GTIVYDQIGY TLLDETIETD VYAELISYLV 

       130        140        150        160        170        180 
EKNLVNQTIF HRGESNYVTE DNKYADFLQK MYSENRSIII RHNEMLKYRT MNKLMIVLDP 

       190        200        210        220        230        240 
SESKTVIGNL KQKFKNKLTI FTTYNGHAEV TKLGHDKYTG INYLLKHYNI SNDQVLVVGD 

       250        260        270        280        290 
AENDIAMLSN FKYSFAVANA TDSAKSHAKC VLPVSHREGA VAYLLKKVFD LKK

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References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Comparative genomics of the neglected human malaria parasite Plasmodium vivax." Carlton J.M., Adams J.H., Silva J.C., Bidwell S.L., Lorenzi H., Caler E., Crabtree J., Angiuoli S.V., Merino E.F., Amedeo P., Cheng Q., Coulson R.M.R., Crabb B.S., del Portillo H.A., Essien K., Feldblyum T.V., Fernandez-Becerra C., Gilson P.R. Fraser-Liggett C.M. Nature 455:757-763(2008) [PubMed: 18843361] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Salvador I EMBL EDL47624.1.
[2]	"Initial Crystallographic Structural Analysis of a putative HAD/COF-like hydrolase from Plasmodium vivax." Structural Genomics of Pathogenic Protozoa Consortium (SGPP) Robien M.A., Bosch J., Hol W.G.J. Submitted (SEP-2005) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.70 ANGSTROMS) IN COMPLEX WITH CALCIUM.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AAKM01000001 Genomic DNA. Translation: EDL47624.1.

RefSeq

XP_001617351.1. XM_001617301.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2B30	X-ray	2.70	A/B/C/D	1-293	[»]

ProteinModelPortal

A5K063.

SMR

A5K063. Positions 9-292.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

5476660.

KEGG

pvx:PVX_123945.

Organism-specific databases

EuPathDB

EupathDB:PVX_123945.

Phylogenomic databases

GeneTree

EPrGT00050000005960.

HOGENOM

HBG629473.

ProtClustDB

CLSZ2432947.

Family and domain databases

InterPro

IPR023214. HAD-like_dom.
IPR013200. HAD-SF_hydro-like_3.
IPR006379. HAD-SF_hydro_IIB.
IPR000150. Hypothet_cof.
[Graphical view]

Gene3D

G3DSA:3.40.50.1000. HAD-like_dom. 2 hits.

Pfam

PF08282. Hydrolase_3. 1 hit.
[Graphical view]

SUPFAM

SSF56784. HAD-like_dom. 1 hit.

TIGRFAMs

TIGR00099. Cof-subfamily. 1 hit.
TIGR01484. HAD-SF-IIB. 1 hit.

ProtoNet

Search...

Entry information

Entry name

A5K063_PLAVS

Accession

Primary (citable) accession number: A5K063

Entry history

Integrated into UniProtKB/TrEMBL:	July 10, 2007
Last sequence update:	July 10, 2007
Last modified:	September 21, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)