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A5J8P3 (A5J8P3_BURMA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylformylglycinamidine cyclo-ligase HAMAP MF_00741 RuleBase RU004370
EC=6.3.3.1 HAMAP MF_00741 RuleBase RU004370
Alternative name(s):
AIR synthase HAMAP MF_00741
AIRS HAMAP MF_00741
Phosphoribosyl-aminoimidazole synthetase HAMAP MF_00741
Gene names
Name:purM HAMAP MF_00741 EMBL EDK53909.1
ORF Names:BMAFMH_0554 EMBL EDK53909.1
OrganismBurkholderia mallei FMH EMBL EDK53909.1
Taxonomic identifier334802 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length351 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. HAMAP MF_00741 RuleBase RU004370 SAAS SAAS004733

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. HAMAP MF_00741 RuleBase RU004371 SAAS SAAS004733

Subcellular location

Cytoplasm By similarity HAMAP MF_00741 SAAS SAAS004733.

Sequence similarities

Belongs to the AIR synthase family. HAMAP MF_00741 RuleBase RU004370

Sequences

Sequence LengthMass (Da)Tools
A5J8P3 [UniParc].

Last modified June 26, 2007. Version 1.
Checksum: BB25FAB317BCFFFA

FASTA35136,913
        10         20         30         40         50         60 
MNPPKSAPDA QGLSYRDAGV DIDAGDALVD KIKPFAKKTL RDGVLGGIGG FGALFEVPKK 

        70         80         90        100        110        120 
YREPVLVSGT DGVGTKLKLA FHLNKHDTVG QDLVAMSVND ILVQGAEPLF FLDYFACGKL 

       130        140        150        160        170        180 
DVETAATVVK GIATGCELAG CALIGGETAE MPGMYPDGEY DLAGFAVGAV EKSKIIDGST 

       190        200        210        220        230        240 
IAEGDVVLGL ASSGIHSNGF SLVRKIIERA NPDLSADFHG RSLADALMAP TRIYVKPLLA 

       250        260        270        280        290        300 
LMEKIAVKGM AHITGGGLVE NIPRVLRDGL TAELDQHAWP LPPLFQWLQQ HGGVADAEMH 

       310        320        330        340        350 
RVFNCGIGMA VIVSAADADD ALRQLADAGE QVWKIGTVRA SREGEAQTVV V

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References

[1]DeShazer D., Woods D.E., Nierman W.C.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: FMH EMBL EDK53909.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		DS264097 Genomic DNA. Translation: EDK53909.1.

3D structure databases

ProteinModelPortalA5J8P3.
SMRA5J8P3. Positions 13-350.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

PATRIC26917458. VBIBurMal45758_3811.

Phylogenomic databases

OMAGIDMIAM.

Family and domain databases

HAMAPMF_00741_B. AIRS_B.
[Tree]
InterProIPR000728. AIR_synth.
IPR010918. AIR_synth_C.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMSSF56042. AIR_synth_C. 1 hit.
SSF55326. PurM_N-like. 1 hit.
TIGRFAMsTIGR00878. PurM. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA5J8P3_BURMA
AccessionPrimary (citable) accession number: A5J8P3
Entry history
Integrated into UniProtKB/TrEMBL: June 26, 2007
Last sequence update: June 26, 2007
Last modified: December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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