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A5IZE2

- A5IZE2_MYCAP

UniProt

A5IZE2 - A5IZE2_MYCAP

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Protein

Thymidine kinase

Gene
tdk, MAG7010
Organism
Mycoplasma agalactiae (strain PG2)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei89 – 891Proton acceptor By similarityUniRule annotation
Metal bindingi145 – 1451Zinc By similarityUniRule annotation
Metal bindingi148 – 1481Zinc By similarityUniRule annotation
Metal bindingi176 – 1761Zinc By similarityUniRule annotation
Metal bindingi179 – 1791Zinc By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 228ATP By similarityUniRule annotation
Nucleotide bindingi88 – 914ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Metal-bindingUniRule annotation, Nucleotide-binding, ZincUniRule annotation

Enzyme and pathway databases

BioCyciMAGA347257:GC07-740-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotationImported
Ordered Locus Names:MAG7010Imported
OrganismiMycoplasma agalactiae (strain PG2)
Taxonomic identifieri347257 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000007065: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi347257.MAG_7010.

Structurei

3D structure databases

ProteinModelPortaliA5IZE2.

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076390.
KOiK00857.
OMAiQAICLSC.
OrthoDBiEOG69D3J2.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

A5IZE2-1 [UniParc]FASTAAdd to Basket

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MYLKNGLGQL EVITGPMFSG KTEELLKRIN ILKIAGINSL VIKPKFDTRF    50
SENEIVSRTG AKHKAINVSS SKEILDHWST KYMCVAIDEV NFMDEDILSV 100
IEELIYKGVK VICSGLDMDF KRRPFDVMAK VLASADSILK LKAVCLECKS 150
DAGFSFRKVK SDELNLLGDS EYEARCRICH IKGEKEKAKM 190
Length:190
Mass (Da):21,403
Last modified:June 26, 2007 - v1
Checksum:i54A7DE9D9C13D69F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU179680 Genomic DNA. Translation: CAL59401.1.
RefSeqiYP_001256839.1. NC_009497.1.

Genome annotation databases

EnsemblBacteriaiCAL59401; CAL59401; MAG7010.
GeneIDi5183928.
KEGGimaa:MAG_7010.
PATRICi32272948. VBIMycAga119067_0748.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU179680 Genomic DNA. Translation: CAL59401.1 .
RefSeqi YP_001256839.1. NC_009497.1.

3D structure databases

ProteinModelPortali A5IZE2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 347257.MAG_7010.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAL59401 ; CAL59401 ; MAG7010 .
GeneIDi 5183928.
KEGGi maa:MAG_7010.
PATRICi 32272948. VBIMycAga119067_0748.

Phylogenomic databases

HOGENOMi HOG000076390.
KOi K00857.
OMAi QAICLSC.
OrthoDBi EOG69D3J2.

Enzyme and pathway databases

BioCyci MAGA347257:GC07-740-MONOMER.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PG2.

Entry informationi

Entry nameiA5IZE2_MYCAP
AccessioniPrimary (citable) accession number: A5IZE2
Entry historyi
Integrated into UniProtKB/TrEMBL: June 26, 2007
Last sequence update: June 26, 2007
Last modified: June 11, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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