SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A5IZB9

- TRMB_MYCAP

UniProt

A5IZB9 - TRMB_MYCAP

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
tRNA (guanine-N(7)-)-methyltransferase
Gene
trmB, MAG6780
Organism
Mycoplasma agalactiae (strain PG2)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei36 – 361S-adenosyl-L-methionine By similarity
Binding sitei61 – 611S-adenosyl-L-methionine By similarity
Binding sitei88 – 881S-adenosyl-L-methionine By similarity
Active sitei109 – 1091 By similarity
Binding sitei109 – 1091S-adenosyl-L-methionine By similarity
Binding sitei113 – 1131Substrate By similarity
Binding sitei145 – 1451Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    S-adenosyl-L-methionine

    Enzyme and pathway databases

    BioCyciMAGA347257:GC07-716-MONOMER.
    UniPathwayiUPA00989.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
    Alternative name(s):
    tRNA (guanine(46)-N(7))-methyltransferase
    tRNA(m7G46)-methyltransferase
    Gene namesi
    Name:trmB
    Ordered Locus Names:MAG6780
    OrganismiMycoplasma agalactiae (strain PG2)
    Taxonomic identifieri347257 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000007065: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 205205tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation
    PRO_1000136356Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi347257.MAG_6780.

    Structurei

    3D structure databases

    ProteinModelPortaliA5IZB9.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni115 – 1206Interaction with RNA Reviewed prediction
    Regioni183 – 1864Substrate binding Reviewed prediction

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0220.
    HOGENOMiHOG000251689.
    KOiK03439.
    OMAiDNVMTEY.
    OrthoDBiEOG6K6VBC.

    Family and domain databases

    Gene3Di3.40.50.150. 1 hit.
    HAMAPiMF_01057. tRNA_methyltr_TrmB.
    InterProiIPR029063. SAM-dependent_MTases-like.
    IPR003358. tRNA_(Gua-N-7)_MeTrfase.
    [Graphical view]
    PfamiPF02390. Methyltransf_4. 1 hit.
    [Graphical view]
    SUPFAMiSSF53335. SSF53335. 1 hit.
    TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
    PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A5IZB9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRLRYDKNAE GKLEMFNYLI KQGDSKILLD DKTVLEIGMG KGEMIVELAK    50
    AHPELNFIGL EKYPTVAAKC IKKANEYNLS NFKILIDDAF KVDEIFEGQC 100
    KVIWLTFSDP WPKARHEKRR LTHPLFLEKY RKILDKDGIL KFKSDNDGLY 150
    EFSLSSLQNS NWRIIDHGID LHNSKYNENN YQTGYERKWS ARGKKINYIF 200
    AQKGE 205
    Length:205
    Mass (Da):24,047
    Last modified:June 26, 2007 - v1
    Checksum:iEC201514A04AA1BE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU179680 Genomic DNA. Translation: CAL59378.1.
    RefSeqiYP_001256816.1. NC_009497.1.

    Genome annotation databases

    EnsemblBacteriaiCAL59378; CAL59378; MAG6780.
    GeneIDi5183975.
    KEGGimaa:MAG_6780.
    PATRICi32272894. VBIMycAga119067_0722.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU179680 Genomic DNA. Translation: CAL59378.1 .
    RefSeqi YP_001256816.1. NC_009497.1.

    3D structure databases

    ProteinModelPortali A5IZB9.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 347257.MAG_6780.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAL59378 ; CAL59378 ; MAG6780 .
    GeneIDi 5183975.
    KEGGi maa:MAG_6780.
    PATRICi 32272894. VBIMycAga119067_0722.

    Phylogenomic databases

    eggNOGi COG0220.
    HOGENOMi HOG000251689.
    KOi K03439.
    OMAi DNVMTEY.
    OrthoDBi EOG6K6VBC.

    Enzyme and pathway databases

    UniPathwayi UPA00989 .
    BioCyci MAGA347257:GC07-716-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.150. 1 hit.
    HAMAPi MF_01057. tRNA_methyltr_TrmB.
    InterProi IPR029063. SAM-dependent_MTases-like.
    IPR003358. tRNA_(Gua-N-7)_MeTrfase.
    [Graphical view ]
    Pfami PF02390. Methyltransf_4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53335. SSF53335. 1 hit.
    TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
    PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PG2.

    Entry informationi

    Entry nameiTRMB_MYCAP
    AccessioniPrimary (citable) accession number: A5IZB9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: June 26, 2007
    Last modified: June 11, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

    Similar proteinsi