A5IU40 (MGT_STAA9) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Monofunctional glycosyltransferase
Short name=MGT
EC=2.4.-.-

Alternative name(s):
Peptidoglycan TGase

Gene names

Name:	mgt
Ordered Locus Names:	SaurJH9_1928

Organism

Staphylococcus aureus (strain JH9) [Complete proteome] [HAMAP]

Taxonomic identifier

359786 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Staphylococcaceae › Staphylococcus › Staphylococcus aureus › Staphylococcus aureus subsp. aureus

Protein attributes

Sequence length	269 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of cell wall peptidoglycan. Responsible for the elongation of the glycan strands using lipid-linked disaccharide-pentapeptide as the substrate By similarity. HAMAP-Rule MF_01434
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_01434
Subcellular location	Cell membrane; Single-pass membrane protein By similarity HAMAP-Rule MF_01434.
Sequence similarities	Belongs to the glycosyltransferase 51 family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	transferase activity, transferring glycosyl groups Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 269	269	Monofunctional glycosyltransferase HAMAP-Rule MF_01434		PRO_1000087440
Regions
	Transmembrane	46 – 66	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	A5IU40 [UniParc]. Last modified June 26, 2007. Version 1. Checksum: D4A9109F47A0976A	FASTA	269	31,428
	10 20 30 40 50 60 MKRSDRYSNS NEHFEHMKHE PHYNTYYQPV GKPPKKKKSK RILLKILLTI LIIIALFIGI 70 80 90 100 110 120 MYFLSTRDNV DELRKIENKS SFVSADNVPE YVKGAFISME DERFYNHHGF DLKGTTRALF 130 140 150 160 170 180 STISDRDVQG GSTITQQVVK NYFYDNDRSF TRKVKELFVA HRVEKQYNKN EILSFYLNNI 190 200 210 220 230 240 YFGDNQYTLE GAANHYFGTT VNKNSTTMSH ITVLQSAILA SKVNAPSVYN INNMSENFTQ 250 260 RVSTNLEKMK QQNYINETQY QQAMSQLNR

References

[1]

"Complete sequence of chromosome of Staphylococcus aureus subsp. aureus JH9." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Tomasz A., Richardson P. Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JH9.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000703 Genomic DNA. Translation: ABQ49713.1.
RefSeq	YP_001247289.1. NC_009487.1.
3D structure databases
ProteinModelPortal	A5IU40.
ModBase	Search...
Protein-protein interaction databases
STRING	359786.SaurJH9_1928.
Protein family/group databases
CAZy	GT51. Glycosyltransferase Family 51.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABQ49713; ABQ49713; SaurJH9_1928.
GeneID	5169662.
KEGG	saj:SaurJH9_1928.
PATRIC	19541768. VBIStaAur42398_2036.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0744.
HOGENOM	HOG000288116.
KO	K04478.
OMA	YISHDEY.
ProtClustDB	PRK13481.
Enzyme and pathway databases
BioCyc	SAUR359786:GJEM-1994-MONOMER.
UniPathway	UPA00219.
Family and domain databases
HAMAP	MF_01434. MGT.
InterPro	IPR001264. Glyco_trans_51. IPR022978. Monofunct_glyco_trans. [Graphical view]
Pfam	PF00912. Transgly. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MGT_STAA9

Accession

Primary (citable) accession number: A5IU40

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	June 26, 2007
Last modified:	May 29, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program