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A5IRX8 (A5IRX8_STAA9) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide deformylase 1 HAMAP MF_00163
Short name=PDF 1 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163
Alternative name(s):
Polypeptide deformylase 1 HAMAP MF_00163
Gene names
Name:def1 HAMAP MF_00163
Ordered Locus Names:SaurJH9_1151
OrganismStaphylococcus aureus (strain JH9) [Complete proteome] [HAMAP] EMBL ABQ48951.1
Taxonomic identifier359786 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length183 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163

Catalytic activity

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181

Cofactor

Binds 1 Fe2+ ion By similarity. HAMAP MF_00163

Sequence similarities

Belongs to the polypeptide deformylase family. HAMAP MF_00163

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1551 By similarity HAMAP MF_00163
Metal binding1111Iron By similarity HAMAP MF_00163
Metal binding1541Iron By similarity HAMAP MF_00163
Metal binding1581Iron By similarity HAMAP MF_00163

Sequences

Sequence LengthMass (Da)Tools
A5IRX8 [UniParc].

Last modified June 26, 2007. Version 1.
Checksum: 32A64066A6FEAB0E

FASTA18320,559
        10         20         30         40         50         60 
MLTMKDIIRD GHPTLRQKAA ELELPLTKEE KETLIAMREF LVNSQDEEIA KRYGLRSGVG 

        70         80         90        100        110        120 
LAAPQINISK RMIAVLIPDD GSGKSYDYML VNPKIVSHSV QEAYLPTGEG CLSVDDNVAG 

       130        140        150        160        170        180 
LVHRHNRITI KAKDIEGNDI QLRLKGYPAI VFQHEIDHLN GVMFYDHIDK NHPLQPHTDA 


VEV

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References

[1]"Complete sequence of chromosome of Staphylococcus aureus subsp. aureus JH9."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Tomasz A., Richardson P.
Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JH9.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000703 Genomic DNA. Translation: ABQ48951.1.
RefSeqYP_001246527.1. NC_009487.1.

3D structure databases

ProteinModelPortalA5IRX8.
SMRA5IRX8. Positions 1-183.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5IRX8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTAT00000017702; EBSTAP00000017121; EBSTAG00000017701.
GeneID5169049.
GenomeReviewsGene locus SaurJH9_1151 in contig CP000703_GR.
KEGGsaj:SaurJH9_1151.
PATRIC19540065. VBIStaAur42398_1224.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0242.
GeneTreeEBGT00050000024244.
HOGENOMHBG665227.
OMAADGEGCL.
ProtClustDBPRK00150.

Enzyme and pathway databases

BioCycSAUR359786:SAURJH9_1151-MONOMER.

Family and domain databases

HAMAPMF_00163. Pep_deformylase.
[Tree]
InterProIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
Gene3DG3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KOK01462.
PANTHERPTHR10458. Fmet_deformylase. 1 hit.
PfamPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFPIRSF004749. Pep_def. 1 hit.
PRINTSPR01576. PDEFORMYLASE.
SUPFAMSSF56420. Fmet_deformylase. 1 hit.
TIGRFAMsTIGR00079. Pept_deformyl. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA5IRX8_STAA9
AccessionPrimary (citable) accession number: A5IRX8
Entry history
Integrated into UniProtKB/TrEMBL: June 26, 2007
Last sequence update: June 26, 2007
Last modified: December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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