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A5IQL2 (GRAR_STAA9) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Response regulator protein GraR
Alternative name(s):
Glycopeptide resistance-associated protein R
Gene names
Name:graR
Ordered Locus Names:SaurJH9_0682
OrganismStaphylococcus aureus (strain JH9) [Complete proteome] [HAMAP]
Taxonomic identifier359786 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length224 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs) By similarity.

Subcellular location

Cytoplasm By similarity.

Post-translational modification

Phosphorylated by GraS By similarity.

Sequence similarities

Contains 1 response regulatory domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 224224Response regulator protein GraR
PRO_0000347898

Regions

Domain2 – 115114Response regulatory

Amino acid modifications

Modified residue5114-aspartylphosphate By similarity

Sequences

Sequence LengthMass (Da)Tools
A5IQL2 [UniParc].

Last modified June 26, 2007. Version 1.
Checksum: 4A636CBAA6FAD233

FASTA22426,066
        10         20         30         40         50         60 
MQILLVEDDN TLFQELKKEL EQWDFNVAGI EDFGKVMDTF ESFNPEIVIL DVQLPKYDGF 

        70         80         90        100        110        120 
YWCRKMREVS NVPILFLSSR DNPMDQVMSM ELGADDYMQK PFYTNVLIAK LQAIYRRVYE 

       130        140        150        160        170        180 
FTAEEKRTLT WQDAVVDLSK DSIQKGDDTI FLSKTEMIIL EILITKKNQI VSRDTIITAL 

       190        200        210        220 
WDDEAFVSDN TLTVNVNRLR KKLSEISMDS AIETKVGKGY MAHE 

« Hide

References

[1]"Complete sequence of chromosome of Staphylococcus aureus subsp. aureus JH9."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Tomasz A., Richardson P.
Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JH9.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000703 Genomic DNA. Translation: ABQ48485.1.
RefSeqYP_001246061.1. NC_009487.1.

3D structure databases

ProteinModelPortalA5IQL2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING359786.SaurJH9_0682.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABQ48485; ABQ48485; SaurJH9_0682.
GeneID5168976.
KEGGsaj:SaurJH9_0682.
PATRIC19539089. VBIStaAur42398_0736.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0745.
HOGENOMHOG000034819.
KOK11630.
OMAMAGESIT.
OrthoDBEOG6G4VQG.

Enzyme and pathway databases

BioCycSAUR359786:GJEM-705-MONOMER.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
InterProIPR011006. CheY-like_superfamily.
IPR001867. Sig_transdc_resp-reg_C.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF00072. Response_reg. 1 hit.
PF00486. Trans_reg_C. 1 hit.
[Graphical view]
SMARTSM00448. REC. 1 hit.
SM00862. Trans_reg_C. 1 hit.
[Graphical view]
SUPFAMSSF46894. SSF46894. 1 hit.
SSF52172. SSF52172. 1 hit.
PROSITEPS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGRAR_STAA9
AccessionPrimary (citable) accession number: A5IQL2
Entry history
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: June 26, 2007
Last modified: May 14, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families