Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Response regulator protein GraR

Gene

graR

Organism
Staphylococcus aureus (strain JH9)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi126 – 224OmpR/PhoB-typePROSITE-ProRule annotationAdd BLAST99

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding, Repressor
Biological processAntibiotic resistance, Transcription, Transcription regulation, Two-component regulatory system, Virulence

Names & Taxonomyi

Protein namesi
Recommended name:
Response regulator protein GraR
Alternative name(s):
Glycopeptide resistance-associated protein R
Gene namesi
Name:graR
Ordered Locus Names:SaurJH9_0682
OrganismiStaphylococcus aureus (strain JH9)
Taxonomic identifieri359786 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003478981 – 224Response regulator protein GraRAdd BLAST224

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei514-aspartylphosphatePROSITE-ProRule annotation1

Post-translational modificationi

Phosphorylated by GraS.By similarity

Keywords - PTMi

Phosphoprotein

Structurei

3D structure databases

ProteinModelPortaliA5IQL2.
SMRiA5IQL2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 115Response regulatoryPROSITE-ProRule annotationAdd BLAST114

Phylogenomic databases

HOGENOMiHOG000034819.
KOiK19078.
OMAiDMVMSMQ.

Family and domain databases

CDDicd00156. REC. 1 hit.
cd00383. trans_reg_C. 1 hit.
Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR011006. CheY-like_superfamily.
IPR001867. OmpR/PhoB-type_DNA-bd.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF00072. Response_reg. 1 hit.
PF00486. Trans_reg_C. 1 hit.
SMARTiView protein in SMART
SM00448. REC. 1 hit.
SM00862. Trans_reg_C. 1 hit.
SUPFAMiSSF46894. SSF46894. 1 hit.
SSF52172. SSF52172. 1 hit.
PROSITEiView protein in PROSITE
PS51755. OMPR_PHOB. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.

Sequencei

Sequence statusi: Complete.

A5IQL2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQILLVEDDN TLFQELKKEL EQWDFNVAGI EDFGKVMDTF ESFNPEIVIL
60 70 80 90 100
DVQLPKYDGF YWCRKMREVS NVPILFLSSR DNPMDQVMSM ELGADDYMQK
110 120 130 140 150
PFYTNVLIAK LQAIYRRVYE FTAEEKRTLT WQDAVVDLSK DSIQKGDDTI
160 170 180 190 200
FLSKTEMIIL EILITKKNQI VSRDTIITAL WDDEAFVSDN TLTVNVNRLR
210 220
KKLSEISMDS AIETKVGKGY MAHE
Length:224
Mass (Da):26,066
Last modified:June 26, 2007 - v1
Checksum:i4A636CBAA6FAD233
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000703 Genomic DNA. Translation: ABQ48485.1.
RefSeqiWP_001166500.1. NC_009487.1.

Genome annotation databases

EnsemblBacteriaiABQ48485; ABQ48485; SaurJH9_0682.
KEGGisaj:SaurJH9_0682.

Similar proteinsi

Entry informationi

Entry nameiGRAR_STAA9
AccessioniPrimary (citable) accession number: A5IQL2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: June 26, 2007
Last modified: August 30, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program