Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A5IQL2

- GRAR_STAA9

UniProt

A5IQL2 - GRAR_STAA9

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Response regulator protein GraR

Gene

graR

Organism
Staphylococcus aureus (strain JH9)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs).By similarity

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW

GO - Biological processi

  1. pathogenesis Source: UniProtKB-KW
  2. phosphorelay signal transduction system Source: UniProtKB-KW
  3. regulation of transcription, DNA-templated Source: UniProtKB-KW
  4. response to antibiotic Source: UniProtKB-KW
  5. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator, Repressor

Keywords - Biological processi

Antibiotic resistance, Transcription, Transcription regulation, Two-component regulatory system, Virulence

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciSAUR359786:GJEM-705-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Response regulator protein GraR
Alternative name(s):
Glycopeptide resistance-associated protein R
Gene namesi
Name:graR
Ordered Locus Names:SaurJH9_0682
OrganismiStaphylococcus aureus (strain JH9)
Taxonomic identifieri359786 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000001984: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 224224Response regulator protein GraRPRO_0000347898Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei51 – 5114-aspartylphosphatePROSITE-ProRule annotation

Post-translational modificationi

Phosphorylated by GraS.By similarity

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi359786.SaurJH9_0682.

Structurei

3D structure databases

ProteinModelPortaliA5IQL2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 115114Response regulatoryPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 response regulatory domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0745.
HOGENOMiHOG000034819.
KOiK11630.
OMAiMAGESIT.
OrthoDBiEOG6G4VQG.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR011006. CheY-like_superfamily.
IPR001867. Sig_transdc_resp-reg_C.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00072. Response_reg. 1 hit.
PF00486. Trans_reg_C. 1 hit.
[Graphical view]
SMARTiSM00448. REC. 1 hit.
SM00862. Trans_reg_C. 1 hit.
[Graphical view]
SUPFAMiSSF46894. SSF46894. 1 hit.
SSF52172. SSF52172. 1 hit.
PROSITEiPS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5IQL2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQILLVEDDN TLFQELKKEL EQWDFNVAGI EDFGKVMDTF ESFNPEIVIL
60 70 80 90 100
DVQLPKYDGF YWCRKMREVS NVPILFLSSR DNPMDQVMSM ELGADDYMQK
110 120 130 140 150
PFYTNVLIAK LQAIYRRVYE FTAEEKRTLT WQDAVVDLSK DSIQKGDDTI
160 170 180 190 200
FLSKTEMIIL EILITKKNQI VSRDTIITAL WDDEAFVSDN TLTVNVNRLR
210 220
KKLSEISMDS AIETKVGKGY MAHE
Length:224
Mass (Da):26,066
Last modified:June 26, 2007 - v1
Checksum:i4A636CBAA6FAD233
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000703 Genomic DNA. Translation: ABQ48485.1.
RefSeqiYP_001246061.1. NC_009487.1.

Genome annotation databases

EnsemblBacteriaiABQ48485; ABQ48485; SaurJH9_0682.
GeneIDi5168976.
KEGGisaj:SaurJH9_0682.
PATRICi19539089. VBIStaAur42398_0736.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000703 Genomic DNA. Translation: ABQ48485.1 .
RefSeqi YP_001246061.1. NC_009487.1.

3D structure databases

ProteinModelPortali A5IQL2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 359786.SaurJH9_0682.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABQ48485 ; ABQ48485 ; SaurJH9_0682 .
GeneIDi 5168976.
KEGGi saj:SaurJH9_0682.
PATRICi 19539089. VBIStaAur42398_0736.

Phylogenomic databases

eggNOGi COG0745.
HOGENOMi HOG000034819.
KOi K11630.
OMAi MAGESIT.
OrthoDBi EOG6G4VQG.

Enzyme and pathway databases

BioCyci SAUR359786:GJEM-705-MONOMER.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR011006. CheY-like_superfamily.
IPR001867. Sig_transdc_resp-reg_C.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00072. Response_reg. 1 hit.
PF00486. Trans_reg_C. 1 hit.
[Graphical view ]
SMARTi SM00448. REC. 1 hit.
SM00862. Trans_reg_C. 1 hit.
[Graphical view ]
SUPFAMi SSF46894. SSF46894. 1 hit.
SSF52172. SSF52172. 1 hit.
PROSITEi PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Staphylococcus aureus subsp. aureus JH9."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.
    , Kim E., Tomasz A., Richardson P.
    Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JH9.

Entry informationi

Entry nameiGRAR_STAA9
AccessioniPrimary (citable) accession number: A5IQL2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: June 26, 2007
Last modified: October 29, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3