A5IM19 (ACYP_THEP1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acylphosphatase
EC=3.6.1.7

Alternative name(s):
Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	Tpet_1228

Organism

Thermotoga petrophila (strain RKU-1 / ATCC BAA-488 / DSM 13995) [Complete proteome] [HAMAP]

Taxonomic identifier

390874 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length	90 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 90	90	Acylphosphatase HAMAP MF_01450		PRO_0000326834
Regions
	Domain	3 – 89	87	Acylphosphatase-like
Sites
	Active site	18	1	By similarity
	Active site	36	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	A5IM19 [UniParc]. Last modified June 26, 2007. Version 1. Checksum: 9A1C09DEAD44C6BE	FASTA	90	10,048
	10 20 30 40 50 60 MKALKIRVEG IVQGVGFRYF TRRVAKSLGV KGYVMNMDDG SVFIHAEGDE NALRRFLNEV 70 80 90 AKGPPAAVVT NVSVEETTPE GYEDFTIKYY

References

[1]

"Complete sequence of Thermotoga petrophila RKU-1." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Mikhailova N., Nelson K., Gogarten J.P., Noll K., Richardson P. Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RKU-1 / ATCC BAA-488 / DSM 13995.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000702 Genomic DNA. Translation: ABQ47242.1.
RefSeq	YP_001244818.1. NC_009486.1.
3D structure databases
ProteinModelPortal	A5IM19.
ModBase	Search...
Protein-protein interaction databases
STRING	A5IM19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5170082.
GenomeReviews	Gene locus Tpet_1228 in contig CP000702_GR.
KEGG	tpt:Tpet_1228.
PATRIC	23945286. VBIThePet65348_1246.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1254.
HOGENOM	HBG750266.
OMA	KRQLTGW.
ProtClustDB	PRK14435.
Enzyme and pathway databases
BioCyc	TPET390874:TPET_1228-MONOMER.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
KO	K01512.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
SUPFAM	SSF54975. Acylphosphatase. 1 hit.
PROSITE	PS00150. ACYLPHOSPHATASE_1. 1 hit. PS00151. ACYLPHOSPHATASE_2. 1 hit. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_THEP1

Accession

Primary (citable) accession number: A5IM19

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	June 26, 2007
Last modified:	January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program