Reviewed, UniProtKB/Swiss-Prot A5ILK6 (APGM_THEP1)

Names and origin

Protein names

Recommended name:
    Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
      Short name=Phosphoglyceromutase
      Short name=BPG-independent PGAM
      Short name=aPGAM
    EC=5.4.2.1

Gene names

Name:	apgM
Ordered Locus Names:	Tpet_1062

Organism

Thermotoga petrophila (strain RKU-1 / ATCC BAA-488 / DSM 13995) [Complete proteome] [HAMAP]

Taxonomic identifier

390874 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length	401 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity.
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 401	401	Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402		PRO_1000068386

Sequences

	Sequence		Length	Mass (Da)
	A5ILK6-1 [UniParc]. Last modified June 26, 2007. Version 1. Checksum: FEA4540275ABFC3C	FASTA	401	44,292
	10 20 30 40 50 60 MFDKQEFVSK LVTEEKAKIV LLVMDGLGDI PVNGKTPLQA ANTPNLDSLA KESDLGQTIP 70 80 90 100 110 120 VLPGITPGSG PGHLSLFGYD PIRYQIGRGI LEALGIGVEV GEKDVVARAN FATWDGKVVL 130 140 150 160 170 180 DRRAGRPATE ESAKVVQLLS EKIKKIEDVE ITFYPGKEHR FVVKFTGEGL GDNVTDADPQ 190 200 210 220 230 240 KEGHPMVWAE GLDEPSKKTA RITNELIKKI AEVLKDNPKI NFALIRGFSK YPDLPKFPQV 250 260 270 280 290 300 YKMKAGAIAT YPMYRGLAKL VGMEIIETGQ TVADEIKTLK ERWNDYDFFY VHVKKTDSYG 310 320 330 340 350 360 EDGKFEEKVK VIEEVDALIP EIVSLNPDVL VITGDHSTPV PLKAHSWHPV PLLIWSKYTR 370 380 390 400 RGLSQAFNEF ECARGTLGTI HASDVMTLAL AYAGKLEKFG A

References

[1]

"Complete sequence of Thermotoga petrophila RKU-1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Mikhailova N., Nelson K., Gogarten J.P., Noll K., Richardson P. Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000702 Genomic DNA. Translation: ABQ47079.1.
RefSeq	YP_001244655.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A5ILK6.
Genome annotation databases
GeneID	5171546.
GenomeReviews	Gene locus Tpet_1062 in contig CP000702_GR.
KEGG	tpt:Tpet_1062.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	ITGDHST.
Family and domain databases
HAMAP	MF_01402. [Tree]
InterPro	IPR004456. APGAM_arc. IPR019304. bisP-indep_Pglycerate_Mutase. IPR006124. Metalloenzyme. [Graphical view]
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
ProDom	PD004704. APGAM_DeoB. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00306. apgM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

APGM_THEP1

Accession

Primary (citable) accession number: A5ILK6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	June 26, 2007
Last modified:	November 3, 2009
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)