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A5ILK6 (APGM_THEP1) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=aPGAM
EC=5.4.2.1
Gene names
Name:apgM
Ordered Locus Names:Tpet_1062
OrganismThermotoga petrophila (strain RKU-1 / ATCC BAA-488 / DSM 13995) [Complete proteome] [HAMAP]
Taxonomic identifier390874 [NCBI]
Taxonomic lineageBacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402_B

Catalytic activity

2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402_B

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402_B

Sequence similarities

Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
   Biological processGlycolysis
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmetal ion binding

Inferred from electronic annotation. Source: InterPro

phosphoglycerate mutase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 401401Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402_B
PRO_1000068386

Sequences

Sequence LengthMass (Da)Tools
A5ILK6 [UniParc].

Last modified June 26, 2007. Version 1.
Checksum: FEA4540275ABFC3C

FASTA40144,292
        10         20         30         40         50         60 
MFDKQEFVSK LVTEEKAKIV LLVMDGLGDI PVNGKTPLQA ANTPNLDSLA KESDLGQTIP 

        70         80         90        100        110        120 
VLPGITPGSG PGHLSLFGYD PIRYQIGRGI LEALGIGVEV GEKDVVARAN FATWDGKVVL 

       130        140        150        160        170        180 
DRRAGRPATE ESAKVVQLLS EKIKKIEDVE ITFYPGKEHR FVVKFTGEGL GDNVTDADPQ 

       190        200        210        220        230        240 
KEGHPMVWAE GLDEPSKKTA RITNELIKKI AEVLKDNPKI NFALIRGFSK YPDLPKFPQV 

       250        260        270        280        290        300 
YKMKAGAIAT YPMYRGLAKL VGMEIIETGQ TVADEIKTLK ERWNDYDFFY VHVKKTDSYG 

       310        320        330        340        350        360 
EDGKFEEKVK VIEEVDALIP EIVSLNPDVL VITGDHSTPV PLKAHSWHPV PLLIWSKYTR 

       370        380        390        400 
RGLSQAFNEF ECARGTLGTI HASDVMTLAL AYAGKLEKFG A

« Hide

References

[1]"Complete sequence of Thermotoga petrophila RKU-1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Nelson K., Gogarten J.P., Noll K., Richardson P.
Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RKU-1 / ATCC BAA-488 / DSM 13995.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000702 Genomic DNA. Translation: ABQ47079.1.
RefSeqYP_001244655.1. NC_009486.1.

3D structure databases

ProteinModelPortalA5ILK6.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5ILK6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5171546.
GenomeReviewsGene locus Tpet_1062 in contig CP000702_GR.
KEGGtpt:Tpet_1062.
PATRIC23944924. VBIThePet65348_1074.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3635.
HOGENOMHBG463247.
OMADIAFRCN.
ProtClustDBPRK04135.

Enzyme and pathway databases

BioCycTPET390874:TPET_1062-MONOMER.

Family and domain databases

HAMAPMF_01402_B. ApgM_B.
[Tree]
InterProIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR023665. ApgAM.
IPR004456. BisP-indep_Pglycerate_Mutase.
IPR006124. Metalloenzyme.
[Graphical view]
Gene3DG3DSA:3.40.720.10. Alk_phosphtse. 2 hits.
KOK15635.
PfamPF01676. Metalloenzyme. 1 hit.
PF10143. PhosphMutase. 1 hit.
[Graphical view]
PIRSFPIRSF006392. IPGAM_arch. 1 hit.
SUPFAMSSF53649. Alkaline_phosphatase_core. 1 hit.
TIGRFAMsTIGR00306. ApgM. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAPGM_THEP1
AccessionPrimary (citable) accession number: A5ILK6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: June 26, 2007
Last modified: January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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