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A5IHI0

- RIMK_LEGPC

UniProt

A5IHI0 - RIMK_LEGPC

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Protein

Probable alpha-L-glutamate ligase

Gene

rimK

Organism
Legionella pneumophila (strain Corby)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Cofactori

Mg2+UniRule annotation, Mn2+UniRule annotationNote: Binds 2 magnesium or manganese ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei142 – 1421ATPUniRule annotation
Binding sitei188 – 1881ATPUniRule annotation
Metal bindingi249 – 2491Magnesium or manganese 1UniRule annotation
Metal bindingi261 – 2611Magnesium or manganese 1UniRule annotation
Metal bindingi261 – 2611Magnesium or manganese 2UniRule annotation
Metal bindingi263 – 2631Magnesium or manganese 2UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi179 – 1802ATPUniRule annotation
Nucleotide bindingi212 – 2143ATPUniRule annotation

GO - Molecular functioni

  1. acid-amino acid ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP
  3. magnesium ion binding Source: UniProtKB-HAMAP
  4. manganese ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. cellular protein modification process Source: InterPro
  2. translation Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Magnesium, Manganese, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciLPNE400673:GCIT-483-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable alpha-L-glutamate ligaseUniRule annotation (EC:6.3.2.-UniRule annotation)
Gene namesi
Name:rimKUniRule annotation
Ordered Locus Names:LPC_2929
OrganismiLegionella pneumophila (strain Corby)
Taxonomic identifieri400673 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella
ProteomesiUP000001569: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 302302Probable alpha-L-glutamate ligasePRO_1000068844Add
BLAST

Proteomic databases

PRIDEiA5IHI0.

Interactioni

Protein-protein interaction databases

STRINGi400673.LPC_2929.

Structurei

3D structure databases

ProteinModelPortaliA5IHI0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini105 – 288184ATP-graspUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the RimK family.UniRule annotation
Contains 1 ATP-grasp domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG0189.
HOGENOMiHOG000293092.
KOiK05844.
OMAiCREPRLY.
OrthoDBiEOG6DZDX8.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPiMF_01552. RimK.
InterProiIPR011761. ATP-grasp.
IPR013651. ATP-grasp_RimK-type.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR016185. PreATP-grasp_dom.
IPR023533. Ribosomal_S6_modifier_RimK.
IPR004666. RpS6_RimK/Lys_biosynth_LsyX.
[Graphical view]
PfamiPF08443. RimK. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00768. rimK_fam. 1 hit.
PROSITEiPS50975. ATP_GRASP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5IHI0-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MKIAILATNP HLYSHKRLKA EAEAAGHEVK IINPLYCYMN VAASNPKVHY
60 70 80 90 100
RGGAPLPHFD AVIPRIGASI TYYGTAVLRH METMGMYTLN ESIAISRSRD
110 120 130 140 150
KFRSLQLLAR KGIPMPLTSF AQSPDDTEDL IHMVGGAPLV IKLLEGTQGK
160 170 180 190 200
GVILADSHQS AVSIINAFKE MHANILVQEF IEESRGTDIR CFVIGEKVVA
210 220 230 240 250
AVKRQAKDGE FRANVHQGGK AVKVKLSPQE RAIAVSAAKT MGLRVAGVDL
260 270 280 290 300
IRSNHGPLVL EINSSPGLEG IEKATNINLA GKIIEYIEKK AKPISSNHRF

HG
Length:302
Mass (Da):32,881
Last modified:June 26, 2007 - v1
Checksum:iDA9A2689AADD2B10
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000675 Genomic DNA. Translation: ABQ56830.1.
RefSeqiYP_001252176.1. NC_009494.2.

Genome annotation databases

EnsemblBacteriaiABQ56830; ABQ56830; LPC_2929.
GeneIDi5182707.
KEGGilpc:LPC_2929.
PATRICi22312455. VBILegPne45588_3031.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000675 Genomic DNA. Translation: ABQ56830.1 .
RefSeqi YP_001252176.1. NC_009494.2.

3D structure databases

ProteinModelPortali A5IHI0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 400673.LPC_2929.

Proteomic databases

PRIDEi A5IHI0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABQ56830 ; ABQ56830 ; LPC_2929 .
GeneIDi 5182707.
KEGGi lpc:LPC_2929.
PATRICi 22312455. VBILegPne45588_3031.

Phylogenomic databases

eggNOGi COG0189.
HOGENOMi HOG000293092.
KOi K05844.
OMAi CREPRLY.
OrthoDBi EOG6DZDX8.

Enzyme and pathway databases

BioCyci LPNE400673:GCIT-483-MONOMER.

Family and domain databases

Gene3Di 3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPi MF_01552. RimK.
InterProi IPR011761. ATP-grasp.
IPR013651. ATP-grasp_RimK-type.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR016185. PreATP-grasp_dom.
IPR023533. Ribosomal_S6_modifier_RimK.
IPR004666. RpS6_RimK/Lys_biosynth_LsyX.
[Graphical view ]
Pfami PF08443. RimK. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00768. rimK_fam. 1 hit.
PROSITEi PS50975. ATP_GRASP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Identification and characterization of a new conjugation/ type IVA secretion system (trb/tra) of L. pneumophila Corby localized on a mobile genomic island."
    Gloeckner G., Albert-Weissenberger C., Weinmann E., Jacobi S., Schunder E., Steinert M., Buchrieser C., Hacker J., Heuner K.
    Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Corby.

Entry informationi

Entry nameiRIMK_LEGPC
AccessioniPrimary (citable) accession number: A5IHI0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: June 26, 2007
Last modified: November 26, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3