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A5IGR8 (DEOB_LEGPC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphopentomutase

EC=5.4.2.7
Alternative name(s):
Phosphodeoxyribomutase
Gene names
Name:deoB
Ordered Locus Names:LPC_2654
OrganismLegionella pneumophila (strain Corby) [Complete proteome] [HAMAP]
Taxonomic identifier400673 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella

Protein attributes

Sequence length407 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Phosphotransfer between the C1 and C5 carbon atoms of pentose By similarity. HAMAP-Rule MF_00740

Catalytic activity

Alpha-D-ribose 1-phosphate = D-ribose 5-phosphate. HAMAP-Rule MF_00740

2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-alpha-D-ribose 5-phosphate. HAMAP-Rule MF_00740

Cofactor

Binds 1 or 2 manganese ions Potential.

Pathway

Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II): step 1/3. HAMAP-Rule MF_00740

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00740.

Sequence similarities

Belongs to the phosphopentomutase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 407407Phosphopentomutase HAMAP-Rule MF_00740
PRO_1000046390

Sites

Metal binding111Manganese By similarity
Metal binding3101Manganese By similarity
Metal binding3461Manganese By similarity
Metal binding3471Manganese By similarity
Metal binding3581Manganese By similarity

Sequences

Sequence LengthMass (Da)Tools
A5IGR8 [UniParc].

Last modified June 26, 2007. Version 1.
Checksum: 251B4A38FDDE8555

FASTA40744,441
        10         20         30         40         50         60 
MTGRVCVLVM DSFGIGASLD AARYGDVGAN TLVHIYEACK RGECDIDGVR KGSLMLPNLA 

        70         80         90        100        110        120 
SKGLYHAAMA SSGLPFIDLS ALAIPSGYYG YAVEQSLGKD TPSGHWEMAG VPVTFEWGYF 

       130        140        150        160        170        180 
PDKPYCFPEE LISEFIKQCN LPGVLGEKHA SGTIIIDELG EEHIRTGKPI VYTSADSVFQ 

       190        200        210        220        230        240 
IAAHEEAFGL QRLYDICKIA RNLVDKYQIG RVIARPFAGK PGSFKRTGNR KDYATPPPEK 

       250        260        270        280        290        300 
TLLDFLKEDG REVIAIGKIA DIYAHQGVTQ EIKADGNMAL FDATLSAMKT APQGSLVFTN 

       310        320        330        340        350        360 
FVDFDSSYGH RRDVAGYAHA LEQFDARLPE LEVLLQPNDM VFIAADHGCD PTFPGSDHTR 

       370        380        390        400 
EHIPVLMFGP QVNSKFIGRR DCFADIGQSI AEHLQLSSPL AHGVSFL 

« Hide

References

[1]"Identification and characterization of a new conjugation/ type IVA secretion system (trb/tra) of L. pneumophila Corby localized on a mobile genomic island."
Gloeckner G., Albert-Weissenberger C., Weinmann E., Jacobi S., Schunder E., Steinert M., Buchrieser C., Hacker J., Heuner K.
Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Corby.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000675 Genomic DNA. Translation: ABQ56568.1.
RefSeqYP_001251914.1. NC_009494.2.

3D structure databases

ProteinModelPortalA5IGR8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING400673.LPC_2654.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABQ56568; ABQ56568; LPC_2654.
GeneID5180479.
KEGGlpc:LPC_2654.
PATRIC22311893. VBILegPne45588_2757.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1015.
HOGENOMHOG000008159.
KOK01839.
OMACHASGTE.
OrthoDBEOG6R5C7J.
ProtClustDBPRK05362.

Enzyme and pathway databases

BioCycLPNE400673:GCIT-752-MONOMER.
UniPathwayUPA00087; UER00173.

Family and domain databases

Gene3D3.30.70.1250. 1 hit.
3.40.720.10. 2 hits.
HAMAPMF_00740. Phosphopentomut.
InterProIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR010045. DeoB.
IPR006124. Metalloenzyme.
IPR024052. Phosphopentomutase_DeoB_cap.
[Graphical view]
PfamPF01676. Metalloenzyme. 1 hit.
[Graphical view]
PIRSFPIRSF001491. Ppentomutase. 1 hit.
SUPFAMSSF143856. SSF143856. 1 hit.
SSF53649. SSF53649. 2 hits.
TIGRFAMsTIGR01696. deoB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDEOB_LEGPC
AccessionPrimary (citable) accession number: A5IGR8
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 26, 2007
Last modified: February 19, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways