Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A5IDL4 (SYR_LEGPC) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:LPC_1515
OrganismLegionella pneumophila (strain Corby) [Complete proteome] [HAMAP]
Taxonomic identifier400673 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaLegionellalesLegionellaceaeLegionella

Protein attributes

Sequence length586 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 586586Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000198913

Regions

Motif128 – 13811"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A5IDL4 [UniParc].

Last modified June 26, 2007. Version 1.
Checksum: 8964E68F09C6E114

FASTA58665,719
        10         20         30         40         50         60 
MKAIIEYLLK QALINLQQSG EMPIDLEIEI KVENAKDPAH GDYATNLALV LAKPCRQAPK 

        70         80         90        100        110        120 
VLAERLVAVI PSDPSVEKIE IAGAGFINFF MRNTARSLII SEILNKGKEF GRGNLGQSQK 

       130        140        150        160        170        180 
VLIEFVSANP TGPLHVGHGR GAAFGATLGN VLKAAGYDVT LEYYVNDAGR QMNILAVSVW 

       190        200        210        220        230        240 
LRYLELAGEP IVFPANGYKG QYVYEIAQEM WSEQGNQFVH PWISVVENLP ADEPEGGDKE 

       250        260        270        280        290        300 
TYIDAIIARA QSLLGKDGFA NFHQHALKTV LDDIKDDLQA FGVRFDSWFS EQSLFEDGSI 

       310        320        330        340        350        360 
EKGIQALKDR GHTYEREGAL WFRATDFGDE KDRVLVRANG QTTYFASDVA YHWNKYDRGF 

       370        380        390        400        410        420 
DRVIDIFGAD HHGYVTRIKT AVKALGHDES ALDVILVQFA ILYRGGDRVQ MSTRSGSFVT 

       430        440        450        460        470        480 
LRELREEVGN DAARYFYVAR KPEQHMDFDL DLAKSESSDN PVYYIQYAHA RICSVLRQLK 

       490        500        510        520        530        540 
ERGLKWDKDM GLKNLDLLEQ QHETTLISLI ARYPEVIQSA AASCEPHQLA YYLRELANGL 

       550        560        570        580 
HSYYNAIQLL CEQEQLRCAR LCLLESVRQV LNNGLAILGV SAPESM 

« Hide

References

[1]"Identification and characterization of a new conjugation/ type IVA secretion system (trb/tra) of L. pneumophila Corby localized on a mobile genomic island."
Gloeckner G., Albert-Weissenberger C., Weinmann E., Jacobi S., Schunder E., Steinert M., Buchrieser C., Hacker J., Heuner K.
Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Corby.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000675 Genomic DNA. Translation: ABQ55464.1.
RefSeqYP_001250810.1. NC_009494.2.

3D structure databases

ProteinModelPortalA5IDL4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING400673.LPC_1515.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABQ55464; ABQ55464; LPC_1515.
GeneID5181332.
KEGGlpc:LPC_1515.
PATRIC22309505. VBILegPne45588_1574.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycLPNE400673:GCIT-2182-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_LEGPC
AccessionPrimary (citable) accession number: A5IDL4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 26, 2007
Last modified: April 16, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries