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A5IAY2 (A5IAY2_LEGPC) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide deformylase 1 HAMAP MF_00163
Short name=PDF 1 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163
Alternative name(s):
Polypeptide deformylase 1 HAMAP MF_00163
Gene names
Name:def EMBL ABQ54532.1
Synonyms:def1 HAMAP MF_00163
Ordered Locus Names:LPC_0547
OrganismLegionella pneumophila (strain Corby) [Complete proteome] [HAMAP]
Taxonomic identifier400673 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Legionellaceae › Legionella

Protein attributes

Sequence length170 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163

Catalytic activity

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181

Cofactor

Binds 1 Fe2+ ion By similarity. HAMAP MF_00163

Sequence similarities

Belongs to the polypeptide deformylase family. HAMAP MF_00163 RuleBase RU003335

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1341 By similarity HAMAP MF_00163
Metal binding911Iron By similarity HAMAP MF_00163
Metal binding1331Iron By similarity HAMAP MF_00163
Metal binding1371Iron By similarity HAMAP MF_00163

Sequences

Sequence LengthMass (Da)Tools
A5IAY2 [UniParc].

Last modified June 26, 2007. Version 1.
Checksum: 5DF901983C6E12B7

FASTA17019,228
        10         20         30         40         50         60 
MAIRKILYLP DERLRKIAKP VETFDESLQT LINDMFDTMY DARGVGLAAP QIGVSLRLSV 

        70         80         90        100        110        120 
IDIVGDKKEQ IVIVNPEIVS SHGEKEFEEG CLSVPGAYDT VVRAEKVTVK ALDRFGKPFE 

       130        140        150        160        170 
ITGEGLLAEC LQHEIDHMNG KLFVDMLSPL KRMMARRKLD KFKRLQARKP

« Hide

References

[1]"Identification and characterization of a new conjugation/ type IVA secretion system (trb/tra) of L. pneumophila Corby localized on a mobile genomic island."
Gloeckner G., Albert-Weissenberger C., Weinmann E., Jacobi S., Schunder E., Steinert M., Buchrieser C., Hacker J., Heuner K.
Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000675 Genomic DNA. Translation: ABQ54532.1.
RefSeqYP_001249878.1. NC_009494.2.

3D structure databases

ProteinModelPortalA5IAY2.
SMRA5IAY2. Positions 2-169.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5IAY2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5182342.
GenomeReviewsGene locus LPC_0547 in contig CP000675_GR.
KEGGlpc:LPC_0547.
PATRIC22307467. VBILegPne45588_0571.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0242.
HOGENOMHBG665227.
OMAGVLFVDY.
ProtClustDBCLSK833499.

Family and domain databases

HAMAPMF_00163. Pep_deformylase.
[Tree]
InterProIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
Gene3DG3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KOK01462.
PANTHERPTHR10458. Fmet_deformylase. 1 hit.
PfamPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFPIRSF004749. Pep_def. 1 hit.
PRINTSPR01576. PDEFORMYLASE.
SUPFAMSSF56420. Fmet_deformylase. 1 hit.
TIGRFAMsTIGR00079. Pept_deformyl. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA5IAY2_LEGPC
AccessionPrimary (citable) accession number: A5IAY2
Entry history
Integrated into UniProtKB/TrEMBL: June 26, 2007
Last sequence update: June 26, 2007
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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