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A5IAB4 (GLSA_LEGPC) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutaminase
EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:LPC_0319
OrganismLegionella pneumophila (strain Corby) [Complete proteome] [HAMAP]
Taxonomic identifier400673 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Legionellaceae › Legionella ›

Protein attributes

Sequence length310 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity.

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 310310Glutaminase HAMAP-Rule MF_00313
PRO_1000079074

Sites

Binding site671Substrate By similarity
Binding site1181Substrate By similarity
Binding site1611Substrate By similarity
Binding site1681Substrate By similarity
Binding site1921Substrate By similarity
Binding site2441Substrate By similarity
Binding site2621Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
A5IAB4 [UniParc].

Last modified June 26, 2007. Version 1.
Checksum: 03B5AE9D78CF47A1

FASTA31033,893
        10         20         30         40         50         60 
MSSKLLTIQL LEELVHAAEL NQEGKTADYI PELANVNQEL TAIAVQPLGE KTLAYSNNPL 

        70         80         90        100        110        120 
HPVTLQSTGK MIPLIGLLEE FGADQLFEWV KVEPSGDDFA SITRLEQFGP KPSNPMLNAG 

       130        140        150        160        170        180 
AIALCSRIPG VGEQQFRWLE HWVQKLFNQR LSINPLVFAS EKRTGNRNRA LAYLLKSRNN 

       190        200        210        220        230        240 
LGADVHETLD LYFALCSYEA MLDQMLYLPA VLANRGQDPD TGEQILSIET CKITLAIMAT 

       250        260        270        280        290        300 
CGLYDETGTH MVKTGMPAKS GVSGYTIAVV PGKAGIVVLS PRVNAKGNSI RGEIMLEGLS 

       310 
KAMGWHFALP

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References

[1]"Identification and characterization of a new conjugation/ type IVA secretion system (trb/tra) of L. pneumophila Corby localized on a mobile genomic island."
Gloeckner G., Albert-Weissenberger C., Weinmann E., Jacobi S., Schunder E., Steinert M., Buchrieser C., Hacker J., Heuner K.
Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Corby.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000675 Genomic DNA. Translation: ABQ54314.1.
RefSeqYP_001249660.1. NC_009494.2.

3D structure databases

ProteinModelPortalA5IAB4.
ModBaseSearch...

Protein-protein interaction databases

STRING400673.LPC_0319.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABQ54314; ABQ54314; LPC_0319.
GeneID5182119.
KEGGlpc:LPC_0319.
PATRIC22306997. VBILegPne45588_0341.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMACKITLAI.
ProtClustDBCLSK832083.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. PBP_transp_fold. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_LEGPC
AccessionPrimary (citable) accession number: A5IAB4
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: June 26, 2007
Last modified: May 1, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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