ID   A5I7Q3_CLOBH            Unreviewed;       795 AA.
AC   A5I7Q3; A7G8Y5;
DT   26-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2007, sequence version 1.
DT   27-MAR-2024, entry version 89.
DE   SubName: Full=Stage II sporulation protein {ECO:0000313|EMBL:CAL85088.1};
GN   OrderedLocusNames=CBO3527 {ECO:0000313|EMBL:CAL85088.1};
OS   Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=441771 {ECO:0000313|EMBL:CAL85088.1, ECO:0000313|Proteomes:UP000001986};
RN   [1] {ECO:0000313|EMBL:CAL85088.1, ECO:0000313|Proteomes:UP000001986}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hall / ATCC 3502 / NCTC 13319 / Type A [Sanger]
RC   {ECO:0000313|Proteomes:UP000001986};
RX   PubMed=17519437; DOI=10.1101/gr.6282807;
RA   Sebaihia M., Peck M.W., Minton N.P., Thomson N.R., Holden M.T.G.,
RA   Mitchell W.J., Carter A.T., Bentley S.D., Mason D.R., Crossman L.,
RA   Paul C.J., Ivens A., Wells-Bennik M.H.J., Davis I.J., Cerdeno-Tarraga A.M.,
RA   Churcher C., Quail M.A., Chillingworth T., Feltwell T., Fraser A.,
RA   Goodhead I., Hance Z., Jagels K., Larke N., Maddison M., Moule S.,
RA   Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M.,
RA   White B., Whithead S., Parkhill J.;
RT   "Genome sequence of a proteolytic (Group I) Clostridium botulinum strain
RT   Hall A and comparative analysis of the clostridial genomes.";
RL   Genome Res. 17:1082-1092(2007).
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DR   EMBL; AM412317; CAL85088.1; -; Genomic_DNA.
DR   RefSeq; WP_012048377.1; NC_009698.1.
DR   RefSeq; YP_001256009.1; NC_009495.1.
DR   RefSeq; YP_001389250.1; NC_009698.1.
DR   AlphaFoldDB; A5I7Q3; -.
DR   GeneID; 5187750; -.
DR   KEGG; cbh:CLC_3491; -.
DR   KEGG; cbo:CBO3527; -.
DR   PATRIC; fig|413999.7.peg.3505; -.
DR   HOGENOM; CLU_017349_1_0_9; -.
DR   Proteomes; UP000001986; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR014221; SpoII_E.
DR   InterPro; IPR045768; SpoIIE_N.
DR   NCBIfam; TIGR02865; spore_II_E; 1.
DR   PANTHER; PTHR43156:SF12; STAGE II SPORULATION PROTEIN E; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   Pfam; PF19732; SpoIIE_N; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   PROSITE; PS51746; PPM_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001986};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        27..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        69..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        120..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        144..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        185..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        212..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        248..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        294..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          576..791
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51746"
SQ   SEQUENCE   795 AA;  90099 MW;  244529D890B1A4F6 CRC64;
     MQYGAELLPY QRLKKIDKQK YKKSINFSSI VNMIIFFISS FLVSRVIFIN NMAPFGIAFL
     LSISRQKEYN KYLFISAVGS IVGYISLINN IGYISLNMLE VVTITLLSYV FKNVEDKKNT
     IIICMIIYLE IFTYKIFVTK ISTTMAMLGA TFEIGCIFPI YYIINYSILC FKNMNTSHLY
     SNEEIVSMAI TLSLVVSGTW GANIAGINLM NLISITMILI IGYVKGSTSA SAIGVAMGAI
     SGLSSNNMMI YISIYGLCGL ISGVFKETGK LMTGISYLVS FLILKFYSNI NYDFKIIEVL
     ISLTLFYIIP NKIYMKMEYE LDYQKKQKNL QENYMDKIKG IITDKLGNFS DVLYNMGNIL
     EKLVDNEKLA MKNKSGALIE NLADRVCSSC NMNHICWKRE GYYTYNALGE LIQNYQENKK
     ELPYEIERKC VKRTQLINNT EDIANNYIIN EMWKKRLSEC REVLANQINT MAYSVEEITK
     EFGQSIRFSN LTEKDIRRML NKNNIKYKDI FCYNNENGRL IINLKIDACT GKQKCVKEIL
     PLINKVTGKL MCVANESCNL DLKNNDCNII FEETPKYHVA SYVNKMAKDG EQCNGDSYSF
     GKLQSGSYMT IISDGMGSGP QAVQESSAVV ELIERFAQSG FSKITAINTI NSIMSIKFSQ
     DEKFSTVDLS NIDLYEGKID FMKVGAVASF IKRGTEVYTI RSKTLPIGVL DKVDIDIETR
     DLKNGDIIVM VSDGVLDYES SSAGKVEWVV EFLKNTTLNN PKEISEELIE NAKKLSKGKV
     KDDMTAIVQK VYSLY
//