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A5I7C5 (A5I7C5_CLOBH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Holo-[acyl-carrier-protein] synthase HAMAP MF_00101
Short name=Holo-ACP synthase HAMAP MF_00101
EC=2.7.8.7 HAMAP MF_00101
Alternative name(s):
4'-phosphopantetheinyl transferase AcpS HAMAP MF_00101
Gene names
Name:acpS HAMAP MF_00101 EMBL CAL84960.1
Ordered Locus Names:CBO3400, CLC_3344
OrganismClostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)
Taxonomic identifier441771 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length126 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein By similarity. HAMAP MF_00101

Catalytic activity

CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein]. HAMAP MF_00101

Cofactor

Magnesium By similarity. HAMAP MF_00101

Subcellular location

Cytoplasm By similarity HAMAP MF_00101.

Sequence similarities

Belongs to the P-Pant transferase superfamily. AcpS family. HAMAP MF_00101

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding81Magnesium By similarity HAMAP MF_00101
Metal binding561Magnesium By similarity HAMAP MF_00101

Sequences

Sequence LengthMass (Da)Tools
A5I7C5 [UniParc].

Last modified June 26, 2007. Version 1.
Checksum: 3083537EA952B97C

FASTA12614,620
        10         20         30         40         50         60 
MIYGIGTDIT EIRRIEKAIT RNKNFINKLF TKNEMDLWEK KNFKLEFIAG RFAAKEAVSK 

        70         80         90        100        110        120 
ALGTGIRDFN FKDIEIINNE LGKPQVILKP KAEDIIRKIS QSYKIHLSIS HEKEYAIAYA 


LLEVFI

« Hide

References

[1]"Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes."
Sebaihia M., Peck M.W., Minton N.P., Thomson N.R., Holden M.T.G., Mitchell W.J., Carter A.T., Bentley S.D., Mason D.R., Crossman L., Paul C.J., Ivens A., Wells-Bennik M.H.J., Davis I.J., Cerdeno-Tarraga A.M., Churcher C., Quail M.A., Chillingworth T. expand/collapse author list , Feltwell T., Fraser A., Goodhead I., Hance Z., Jagels K., Larke N., Maddison M., Moule S., Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M., White B., Whithead S., Parkhill J.
Genome Res. 17:1082-1092(2007) [PubMed: 17519437] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Hall / ATCC 3502 / NCTC 13319 / Type A [Sanger].
[2]"Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids."
Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C., Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S.
PLoS ONE 2:E1271-E1271(2007) [PubMed: 18060065] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Hall / ATCC 3502 / NCTC 13319 / Type A [Los Alamos].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000727 Genomic DNA. Translation: ABS39111.1.
AM412317 Genomic DNA. Translation: CAL84960.1.
RefSeqYP_001255882.1. NC_009495.1.
YP_001389124.1. NC_009698.1.

3D structure databases

ProteinModelPortalA5I7C5.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5I7C5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5187865.
5400539.
GenomeReviewsGene locus CBO3400 in contig AM412317_GR.
Gene locus CLC_3344 in contig CP000727_GR.
KEGGcbh:CLC_3344.
cbo:CBO3400.
PATRIC19368929. VBICloBot22612_3376.

Phylogenomic databases

eggNOGCOG0736.
HOGENOMHBG734479.
OMAVHVSITH.
ProtClustDBCLSK972423.

Family and domain databases

HAMAPMF_00101. AcpS.
[Tree]
InterProIPR008278. 4-PPantetheinyl_Trfase.
IPR002582. ACPS.
IPR000700. PAS-assoc_C.
IPR004568. PPantethiene-prot_Trfase.
[Graphical view]
Gene3DG3DSA:3.90.470.20. G3DSA:3.90.470.20. 1 hit.
KOK00997.
PfamPF01648. ACPS. 1 hit.
[Graphical view]
ProDomPD004282. PPantethiene-prot_Trfase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF56214. 4-PPT_transf. 1 hit.
TIGRFAMsTIGR00516. AcpS. 1 hit.
TIGR00556. Pantethn_trn. 1 hit.
PROSITEPS50113. PAC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5I7C5_CLOBH
AccessionPrimary (citable) accession number: A5I7C5
Secondary accession number(s): A7G8K9
Entry history
Integrated into UniProtKB/TrEMBL: June 26, 2007
Last sequence update: June 26, 2007
Last modified: December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info