A5I6X4 (A5I6X4_CLOBH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2-hydroxyacyl-CoA dehydratase beta-subunit EMBL CAL84806.1

Submitted name:
2-hydroxyglutaryl-CoA dehydratase, D-component EMBL ABS37335.1
EC=4.2.1.- EMBL ABS37335.1

Gene names

Ordered Locus Names:

CBO3244, CLC_3155

Organism

Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)

Taxonomic identifier

441771 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	419 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Lyase EMBL ABS37335.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	lyase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5I6X4 [UniParc]. Last modified June 26, 2007. Version 1. Checksum: C4E77F912802495F	FASTA	419	47,866
	10 20 30 40 50 60 MGDYRKLWTD LGVNLEKHDQ LCAVLPELYG STYLTQENRP EGMNYFNFVV SEVHGLRIQE 70 80 90 100 110 120 LDEHRKKGGK VVGTFCVFVP EEIIVAAKAI SVGLCAGSQF WIEDGEKVLP RNMCPLIKAF 130 140 150 160 170 180 MGAKIGGTCP YFQSCDMVIG ETTCDGKKKA WEILDEYVPV HVMDLPQMKR DKDFKKWGEE 190 200 210 220 230 240 INDLIKKVEE ITGNKITVEA LKEGIRVTNA KRRALKRLYD LRKYKPSPIS GLDCLLITQI 250 260 270 280 290 300 AFYDDPKRFT EKVHELCDEL EERIKNSQES NKKRILITGT PMALPNWKLH SIIESLDAEV 310 320 330 340 350 360 VVEETCTGTR YFEGEVSEEG ETLEELIKNL ADRYLNINCA CFTPNTGRID DIIKYTKEYE 370 380 390 400 410 ADGVIDTNLS FCHTYAAEHR DVEAKLKEEN ISIMHIETDY STEDSGQIKT RVEAFLEMI

References

[1]

"Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes." Sebaihia M., Peck M.W., Minton N.P., Thomson N.R., Holden M.T.G., Mitchell W.J., Carter A.T., Bentley S.D., Mason D.R., Crossman L., Paul C.J., Ivens A., Wells-Bennik M.H.J., Davis I.J., Cerdeno-Tarraga A.M., Churcher C., Quail M.A., Chillingworth T. , Feltwell T., Fraser A., Goodhead I., Hance Z., Jagels K., Larke N., Maddison M., Moule S., Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M., White B., Whithead S., Parkhill J. Genome Res. 17:1082-1092(2007) [PubMed: 17519437] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hall / ATCC 3502 / NCTC 13319 / Type A [Sanger].

[2]

"Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids." Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C., Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S. PLoS ONE 2:E1271-E1271(2007) [PubMed: 18060065] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hall / ATCC 3502 / NCTC 13319 / Type A [Los Alamos].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000727 Genomic DNA. Translation: ABS37335.1. AM412317 Genomic DNA. Translation: CAL84806.1.
RefSeq	YP_001255734.1. NC_009495.1. YP_001388974.1. NC_009698.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A5I6X4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5185500. 5399407.
GenomeReviews	Gene locus CBO3244 in contig AM412317_GR. Gene locus CLC_3155 in contig CP000727_GR.
KEGG	cbh:CLC_3155. cbo:CBO3244.
PATRIC	19368577. VBICloBot22612_3223.
Phylogenomic databases
eggNOG	COG1775.
HOGENOM	HBG304933.
OMA	ENTCDGK.
ProtClustDB	CLSK900553.
Family and domain databases
InterPro	IPR010327. HGD-D. [Graphical view]
Pfam	PF06050. HGD-D. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5I6X4_CLOBH

Accession

Primary (citable) accession number: A5I6X4
Secondary accession number(s): A7G859

Entry history

Integrated into UniProtKB/TrEMBL:	June 26, 2007
Last sequence update:	June 26, 2007
Last modified:	December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)