A5I4M2 (RL19_CLOBH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L19

Gene names

Name:	rplS
Ordered Locus Names:	CBO2444, CLC_2292

Organism

Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)

Taxonomic identifier

441771 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	114 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site By similarity. HAMAP MF_00402
Sequence similarities	Belongs to the ribosomal protein L19P family.

Ontologies

Keywords
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 114	114	50S ribosomal protein L19 HAMAP MF_00402		PRO_1000049661

Sequences

	Sequence		Length	Mass (Da)
	A5I4M2 [UniParc]. Last modified June 26, 2007. Version 1. Checksum: 1141FC0A8457901C	FASTA	114	13,106
	10 20 30 40 50 60 MLEVIKAIEA EQVRSDLPEF NVGDTVKVHQ KIKEGTRERV QVFEGTVLKR QNGGARETFT 70 80 90 100 110 VRRVAYNVAV EKTFPVNSPL IEKIQVVRKG KVRRAKLYYL RDRVGKAAKV KERI

References

[1]

"Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes." Sebaihia M., Peck M.W., Minton N.P., Thomson N.R., Holden M.T.G., Mitchell W.J., Carter A.T., Bentley S.D., Mason D.R., Crossman L., Paul C.J., Ivens A., Wells-Bennik M.H.J., Davis I.J., Cerdeno-Tarraga A.M., Churcher C., Quail M.A., Chillingworth T. , Feltwell T., Fraser A., Goodhead I., Hance Z., Jagels K., Larke N., Maddison M., Moule S., Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M., White B., Whithead S., Parkhill J. Genome Res. 17:1082-1092(2007) [PubMed: 17519437] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hall / ATCC 3502 / NCTC 13319 / Type A.

[2]

"Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids." Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C., Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S. PLoS ONE 2:E1271-E1271(2007) [PubMed: 18060065] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hall / ATCC 3502 / NCTC 13319 / Type A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000727 Genomic DNA. Translation: ABS36445.1. AM412317 Genomic DNA. Translation: CAL83994.1.
RefSeq	YP_001254943.1. NC_009495.1. YP_001388136.1. NC_009698.1.
3D structure databases
ProteinModelPortal	A5I4M2.
ModBase	Search...
Protein-protein interaction databases
STRING	A5I4M2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5186699. 5400441.
GenomeReviews	Gene locus CBO2444 in contig AM412317_GR. Gene locus CLC_2292 in contig CP000727_GR.
KEGG	cbh:CLC_2292. cbo:CBO2444.
PATRIC	19366957. VBICloBot22612_2421.
Phylogenomic databases
eggNOG	COG0335.
HOGENOM	HBG611003.
OMA	FPLHSPI.
ProtClustDB	PRK05338.
Enzyme and pathway databases
BioCyc	CBOT36826:CBO2444-MONOMER. CBOT441771:CLC_2292-MONOMER.
Family and domain databases
HAMAP	MF_00402. Ribosomal_L19. [Tree]
InterPro	IPR001857. Ribosomal_L19. IPR018257. Ribosomal_L19_CS. IPR008991. Translation_prot_SH3-like. [Graphical view]
KO	K02884.
PANTHER	PTHR15680. Ribosomal_L19. 1 hit.
Pfam	PF01245. Ribosomal_L19. 1 hit. [Graphical view]
PIRSF	PIRSF002191. Ribosomal_L19. 1 hit.
PRINTS	PR00061. RIBOSOMALL19.
SUPFAM	SSF50104. Transl_SH3_like. 1 hit.
TIGRFAMs	TIGR01024. RplS_bact. 1 hit.
PROSITE	PS01015. RIBOSOMAL_L19. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL19_CLOBH

Accession

Primary (citable) accession number: A5I4M2
Secondary accession number(s): A7G5S1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	June 26, 2007
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program