A5I446 (A5I446_CLOBH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Superoxide dismutase RuleBase RU000414
EC=1.15.1.1 RuleBase RU000414

Gene names

Name:	sodA EMBL ABS39066.1
Ordered Locus Names:	CBO2277 EMBL CAL83817.1, CLC_2204 EMBL ABS39066.1

Organism

Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A) [Reference proteome] [HAMAP]

Taxonomic identifier

441771 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium › Clostridium botulinum › Clostridium botulinum A

Protein attributes

Sequence length	198 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity.
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2.
Sequence similarities	Belongs to the iron/manganese superoxide dismutase family. RuleBase RU004477

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU000414 EMBL ABS39066.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: InterPro superoxide dismutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5I446 [UniParc]. Last modified June 26, 2007. Version 1. Checksum: B1BFA3D73689B8F3	FASTA	198	23,336
	10 20 30 40 50 60 MAHTLPNLNY DYNALEPHYD EQTLKIHHDI HHKAYVDGLN KAEQKLQEAR ESGDFALIKH 70 80 90 100 110 120 WEKEIAFHGS GHILHTLFWE NMAPNGNLNP EGSAIERIKQ DFGDYEKFKK QFTEAAIAVE 130 140 150 160 170 180 GSGWTILAWN PMFQKLVILQ VEKHQNLTQW GVVPLLILDL WEHAYYLKYQ NRRAEFINAW 190 WNIVNWDIVN TRYDNAIK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes." Sebaihia M., Peck M.W., Minton N.P., Thomson N.R., Holden M.T., Mitchell W.J., Carter A.T., Bentley S.D., Mason D.R., Crossman L., Paul C.J., Ivens A., Wells-Bennik M.H., Davis I.J., Cerdeno-Tarraga A.M., Churcher C., Quail M.A., Chillingworth T. , Feltwell T., Fraser A., Goodhead I., Hance Z., Jagels K., Larke N., Maddison M., Moule S., Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M., White B., Whithead S., Parkhill J. Genome Res. 17:1082-1092(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 3502 EMBL CAL83817.1 and Hall / ATCC 3502 / NCTC 13319 / Type A [Sanger].
[2]	"Analysis of the Neurotoxin Complex Genes in Clostridium botulinum A1-A4 and B1 Strains: BoNT/A3, /Ba4 and /B1 Clusters Are Located within Plasmids." Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C., Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S. PLoS ONE 2:E1271-E1271(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hall EMBL ABS39066.1 and Hall / ATCC 3502 / NCTC 13319 / Type A [Los Alamos].
[3]	Shrivastava S., Brinkac L.M., Dodson R.J., Harkins D.M., Durkin A.S., Sutton G. Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Hall EMBL ABS39066.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000727 Genomic DNA. Translation: ABS39066.1. AM412317 Genomic DNA. Translation: CAL83817.1.
RefSeq	YP_001254769.1. NC_009495.1. YP_001388048.1. NC_009698.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	413999.CBO2277.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABS39066; ABS39066; CLC_2204.
GeneID	5187439. 5400103.
KEGG	cbh:CLC_2204. cbo:CBO2277.
PATRIC	19366615. VBICloBot22612_2250.
Phylogenomic databases
eggNOG	COG0605.
HOGENOM	HOG000013583.
KO	K04564.
OMA	WNNMKKD.
ProtClustDB	CLSK911931.
Enzyme and pathway databases
BioCyc	CBOT413999:GJ72-2341-MONOMER. CBOT441771:GIWX-2170-MONOMER.
Family and domain databases
InterPro	IPR001189. Mn/Fe_SOD. IPR019833. Mn/Fe_SOD_BS. IPR019832. Mn/Fe_SOD_C. IPR019831. Mn/Fe_SOD_N. [Graphical view]
PANTHER	PTHR11404. PTHR11404. 1 hit.
Pfam	PF02777. Sod_Fe_C. 1 hit. PF00081. Sod_Fe_N. 1 hit. [Graphical view]
PIRSF	PIRSF000349. SODismutase. 1 hit.
PRINTS	PR01703. MNSODISMTASE.
SUPFAM	SSF46609. SODismutase. 1 hit. SSF54719. SODismutase. 1 hit.
PROSITE	PS00088. SOD_MN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5I446_CLOBH

Accession

Primary (citable) accession number: A5I446
Secondary accession number(s): A7G5I3

Entry history

Integrated into UniProtKB/TrEMBL:	June 26, 2007
Last sequence update:	June 26, 2007
Last modified:	May 1, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)