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Protein

Glutamate decarboxylase

Gene

gadA

Organism
Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciCBOT441771:G1G97-1793-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:gadAImported
Ordered Locus Names:CBO1917Imported
OrganismiClostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)Imported
Taxonomic identifieri441771 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000001986 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei278N6-(pyridoxal phosphate)lysineUniRule annotation1

Structurei

3D structure databases

ProteinModelPortaliA5I341
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000070228
KOiK01580
OMAiRPNLVMG

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR010107 Glutamate_decarboxylase
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR43321 PTHR43321, 1 hit
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR01788 Glu-decarb-GAD, 1 hit

Sequencei

Sequence statusi: Complete.

A5I341-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLYSSKNKQS NDTYATPIFG ITKDKYSIPK YKINENSIAP NIAYRMIKDE
60 70 80 90 100
LMNEGNARLN LATFCQTYME DKATKLMAET LQKNAIDKSE YPQTAEIENR
110 120 130 140 150
CVNIISDLWN VPKDMNFLGT STVGSSEACM LGGMSMKFRW RDQAKKLGID
160 170 180 190 200
INKKKPNLVI SSGYQVCWEK FCVYWDIEMR TVPMDEDNLS LNIDKILDYV
210 220 230 240 250
DEYTIGIIGI LGITYTGKFD DIKALDDAIE KYNSNHDIKV YIHVDAASGG
260 270 280 290 300
FFTPFINPEI LWDFRLKNVV SINASGHKYG LVYPGIGWIL WKDQEYLPKD
310 320 330 340 350
LIFEVSYLGG KMPTLAINFS RSGSQIIGQY YNFLRFGFEG YKKIHERTKE
360 370 380 390 400
VAMYISKELE ATGLFSIYND GSNLPIVCYK LKEQSKVKWN LYDLSDRLAM
410 420 430 440 450
KGWQIPAYPL PENLNHIIIQ RIVCRSDLGY NLAELLIKDF KTAINDLNNA
460
HILFHEEENQ GIYGFTH
Length:467
Mass (Da):53,660
Last modified:June 26, 2007 - v1
Checksum:i533231CB09C8E733
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM412317 Genomic DNA Translation: CAL83458.1
RefSeqiWP_011986457.1, NC_009698.1
YP_001254419.1, NC_009495.1
YP_001387716.1, NC_009698.1

Genome annotation databases

GeneIDi5186172
5400624
KEGGicbh:CLC_1861
cbo:CBO1917
PATRICifig|413999.7.peg.1888

Similar proteinsi

Entry informationi

Entry nameiA5I341_CLOBH
AccessioniPrimary (citable) accession number: A5I341
Secondary accession number(s): A7G4K1
Entry historyiIntegrated into UniProtKB/TrEMBL: June 26, 2007
Last sequence update: June 26, 2007
Last modified: April 25, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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