A5I341 (A5I341_CLOBH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glutamate decarboxylase EMBL ABS39064.1
EC=4.1.1.15 EMBL ABS39064.1

Submitted name:
Glutamate decarboxylase alpha EMBL CAL83458.1
EC=4.1.1.15 EMBL CAL83458.1

Gene names

Name:	gadA EMBL CAL83458.1
Ordered Locus Names:	CBO1917 EMBL CAL83458.1, CLC_1861 EMBL ABS39064.1

Organism

Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A) [Reference proteome] [HAMAP]

Taxonomic identifier

441771 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium › Clostridium botulinum › Clostridium botulinum A

Protein attributes

Sequence length	467 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000382
Sequence similarities	Belongs to the group II decarboxylase family. RuleBase RU000382

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000382
Molecular function	Lyase RuleBase RU000382 EMBL CAL83458.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glutamate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	glutamate decarboxylase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5I341 [UniParc]. Last modified June 26, 2007. Version 1. Checksum: 533231CB09C8E733	FASTA	467	53,660
	10 20 30 40 50 60 MLYSSKNKQS NDTYATPIFG ITKDKYSIPK YKINENSIAP NIAYRMIKDE LMNEGNARLN 70 80 90 100 110 120 LATFCQTYME DKATKLMAET LQKNAIDKSE YPQTAEIENR CVNIISDLWN VPKDMNFLGT 130 140 150 160 170 180 STVGSSEACM LGGMSMKFRW RDQAKKLGID INKKKPNLVI SSGYQVCWEK FCVYWDIEMR 190 200 210 220 230 240 TVPMDEDNLS LNIDKILDYV DEYTIGIIGI LGITYTGKFD DIKALDDAIE KYNSNHDIKV 250 260 270 280 290 300 YIHVDAASGG FFTPFINPEI LWDFRLKNVV SINASGHKYG LVYPGIGWIL WKDQEYLPKD 310 320 330 340 350 360 LIFEVSYLGG KMPTLAINFS RSGSQIIGQY YNFLRFGFEG YKKIHERTKE VAMYISKELE 370 380 390 400 410 420 ATGLFSIYND GSNLPIVCYK LKEQSKVKWN LYDLSDRLAM KGWQIPAYPL PENLNHIIIQ 430 440 450 460 RIVCRSDLGY NLAELLIKDF KTAINDLNNA HILFHEEENQ GIYGFTH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes." Sebaihia M., Peck M.W., Minton N.P., Thomson N.R., Holden M.T., Mitchell W.J., Carter A.T., Bentley S.D., Mason D.R., Crossman L., Paul C.J., Ivens A., Wells-Bennik M.H., Davis I.J., Cerdeno-Tarraga A.M., Churcher C., Quail M.A., Chillingworth T. , Feltwell T., Fraser A., Goodhead I., Hance Z., Jagels K., Larke N., Maddison M., Moule S., Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M., White B., Whithead S., Parkhill J. Genome Res. 17:1082-1092(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 3502 EMBL CAL83458.1 and Hall / ATCC 3502 / NCTC 13319 / Type A [Sanger].
[2]	"Analysis of the Neurotoxin Complex Genes in Clostridium botulinum A1-A4 and B1 Strains: BoNT/A3, /Ba4 and /B1 Clusters Are Located within Plasmids." Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C., Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S. PLoS ONE 2:E1271-E1271(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hall EMBL ABS39064.1 and Hall / ATCC 3502 / NCTC 13319 / Type A [Los Alamos].
[3]	Shrivastava S., Brinkac L.M., Dodson R.J., Harkins D.M., Durkin A.S., Sutton G. Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Hall EMBL ABS39064.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000727 Genomic DNA. Translation: ABS39064.1. AM412317 Genomic DNA. Translation: CAL83458.1.
RefSeq	YP_001254419.1. NC_009495.1. YP_001387716.1. NC_009698.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	413999.CBO1917.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABS39064; ABS39064; CLC_1861.
GeneID	5186172. 5400624.
KEGG	cbh:CLC_1861. cbo:CBO1917.
PATRIC	19365891. VBICloBot22612_1888.
Phylogenomic databases
eggNOG	COG0076.
HOGENOM	HOG000070228.
KO	K01580.
OMA	PMDKEHM.
ProtClustDB	CLSK876864.
Enzyme and pathway databases
BioCyc	CBOT413999:GJ72-1980-MONOMER. CBOT441771:GIWX-1829-MONOMER.
Family and domain databases
Gene3D	3.40.640.10. 1 hit.
InterPro	IPR010107. Glutamate_decarboxylase. IPR002129. PyrdxlP-dep_de-COase. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
PANTHER	PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfam	PF00282. Pyridoxal_deC. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5I341_CLOBH

Accession

Primary (citable) accession number: A5I341
Secondary accession number(s): A7G4K1

Entry history

Integrated into UniProtKB/TrEMBL:	June 26, 2007
Last sequence update:	June 26, 2007
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)