A5I303 (A5I303_CLOBH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Probable inorganic polyphosphate/ATP-NAD kinase 1 HAMAP MF_00361
Short name=Poly(P)/ATP NAD kinase 1 HAMAP MF_00361
EC=2.7.1.23 HAMAP MF_00361

Gene names

Name:	ppnK1 HAMAP MF_00361
Ordered Locus Names:	CBO1879

Organism

Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)

Taxonomic identifier

441771 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	281 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361 SAAS SAAS002504
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361 SAAS SAAS002504
Cofactor	Divalent metal ions By similarity. HAMAP MF_00361 SAAS SAAS002504
Subcellular location	Cytoplasm By similarity HAMAP MF_00361 SAAS SAAS002504.
Sequence similarities	Belongs to the NAD kinase family. HAMAP MF_00361

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00361 SAAS SAAS002504
Ligand	ATP-binding HAMAP MF_00361 SAAS SAAS002504 NAD HAMAP MF_00361 SAAS SAAS002504 NADP HAMAP MF_00361 SAAS SAAS002504 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00361 SAAS SAAS002504 EMBL CAL83420.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5I303 [UniParc]. Last modified June 26, 2007. Version 1. Checksum: 9DEB0A8B8EE1BE5D	FASTA	281	31,706
	10 20 30 40 50 60 MKNIGININT DKDISRNILD KIFQYIHEEC SEAKIKVFYD SKGLDNEESR ALDAVMVLGG 70 80 90 100 110 120 DGTILGTARA LAKYDVPIFG INRGHLGFLA EIELEDCKKA IKNLFKGQYK IEDRIMLKCD 130 140 150 160 170 180 LKGIDKKDDF LALNDIVLTK GNLSRIVKYS IYVDDVWYTT FVADGVIVST PTGSTAYSLS 190 200 210 220 230 240 AGGPIVYPDL DVLEIAPICP HSLGIRPILL NGNSKINIRV LKKYEDPVLT IDGQRYKKVT 250 260 270 280 VNEVTISKSE YKCRLIKFKD KDYFKILRTK ISYRSRECEG E

References

[1]

"Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes." Sebaihia M., Peck M.W., Minton N.P., Thomson N.R., Holden M.T.G., Mitchell W.J., Carter A.T., Bentley S.D., Mason D.R., Crossman L., Paul C.J., Ivens A., Wells-Bennik M.H.J., Davis I.J., Cerdeno-Tarraga A.M., Churcher C., Quail M.A., Chillingworth T. , Feltwell T., Fraser A., Goodhead I., Hance Z., Jagels K., Larke N., Maddison M., Moule S., Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M., White B., Whithead S., Parkhill J. Genome Res. 17:1082-1092(2007) [PubMed: 17519437] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hall / ATCC 3502 / NCTC 13319 / Type A [Sanger].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM412317 Genomic DNA. Translation: CAL83420.1.
RefSeq	YP_001254381.1. NC_009495.1.
3D structure databases
ProteinModelPortal	A5I303.
ModBase	Search...
Protein-protein interaction databases
STRING	A5I303.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5186134.
GenomeReviews	Gene locus CBO1879 in contig AM412317_GR.
KEGG	cbo:CBO1879.
PATRIC	19365817. VBICloBot22612_1851.
Phylogenomic databases
eggNOG	COG0061.
HOGENOM	HBG713904.
OMA	KLGWGLP.
ProtClustDB	CLSK961137.
Family and domain databases
HAMAP	MF_00361. NAD_kinase. [Tree]
InterPro	IPR016064. ATP-NAD_kinase_PpnK-typ. IPR017438. ATP-NAD_kinase_PpnK-typ_a/b. IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. polyP/ATP_NADK_prd. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit. G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
KO	K00858.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
SUPFAM	SSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5I303_CLOBH

Accession

Primary (citable) accession number: A5I303

Entry history

Integrated into UniProtKB/TrEMBL:	June 26, 2007
Last sequence update:	June 26, 2007
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)