A5I148 (A5I148_CLOBH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glycosyl hydrolase, family 18 EMBL ABS36498.1

Submitted name:
Putative chitinase/spore peptidoglycan hydrolase EMBL CAL82759.1

Gene names

Ordered Locus Names:

CBO1212, CLC_1253

Organism

Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)

Taxonomic identifier

441771 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	504 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Glycosidase RuleBase RU000489 Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cell wall macromolecule catabolic process Inferred from electronic annotation. Source: InterPro chitin catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	cation binding Inferred from electronic annotation. Source: InterPro chitinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5I148 [UniParc]. Last modified June 26, 2007. Version 1. Checksum: DB74FE4707848B26	FASTA	504	57,345
	10 20 30 40 50 60 MWRQPNISYI VKPGDSLFTI ARSYGITVEQ LKEYNGLVSN DLYVGQQIFI PISIYKVQRG 70 80 90 100 110 120 DSLYYIAKKF DTTVESLMVL NNLDSINLNI GQILYIPLYT EAIMKVEDGN IRSQPSINSK 130 140 150 160 170 180 ILYKMAKGAK LPIIGVYKDF YKIKLFNGNE GFVSKAIVDF KTYGNMKPVV AVDGFYTLEE 190 200 210 220 230 240 GETLPSSYES FVTNINLISE ICLFMFRIDP SDATAIEKFG DFTDEYVKEL VNIAHRNNVR 250 260 270 280 290 300 ALAVVHNLLY RPGGTTKAKD LVKSLVSTRE NRQIFINNLI SLIEKYNFDG VNIDIEDVYI 310 320 330 340 350 360 EDKDNLSSLY LEMGREFRRK GYFLSASIPS RVSDEPFNPF SDPFDYRIIG SAVDEFIVML 370 380 390 400 410 420 YNEHGWPGSG PGPVVSIGWM NRVLNYTITR VPRNKVVAAV SVFGFDFNLT TGRNTYVTYA 430 440 450 460 470 480 GAIEIAKRYG KDIIFDEETK TPMFSYVDEN GNNHEVWFEN AESIYAKAEL AFNKGIKGIA 490 500 LWRLGMEDNK IWDSMKKDIV VKMA

References

[1]

"Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes." Sebaihia M., Peck M.W., Minton N.P., Thomson N.R., Holden M.T.G., Mitchell W.J., Carter A.T., Bentley S.D., Mason D.R., Crossman L., Paul C.J., Ivens A., Wells-Bennik M.H.J., Davis I.J., Cerdeno-Tarraga A.M., Churcher C., Quail M.A., Chillingworth T. , Feltwell T., Fraser A., Goodhead I., Hance Z., Jagels K., Larke N., Maddison M., Moule S., Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M., White B., Whithead S., Parkhill J. Genome Res. 17:1082-1092(2007) [PubMed: 17519437] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hall / ATCC 3502 / NCTC 13319 / Type A [Sanger].

[2]

"Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids." Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C., Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S. PLoS ONE 2:E1271-E1271(2007) [PubMed: 18060065] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hall / ATCC 3502 / NCTC 13319 / Type A [Los Alamos].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000727 Genomic DNA. Translation: ABS36498.1. AM412317 Genomic DNA. Translation: CAL82759.1.
RefSeq	YP_001253735.1. NC_009495.1. YP_001387120.1. NC_009698.1.
3D structure databases
ProteinModelPortal	A5I148.
ModBase	Search...
Protein-protein interaction databases
STRING	A5I148.
Protein family/group databases
CAZy	CBM50. Carbohydrate-Binding Module Family 50. GH18. Glycoside Hydrolase Family 18.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5185467. 5399736.
GenomeReviews	Gene locus CBO1212 in contig AM412317_GR. Gene locus CLC_1253 in contig CP000727_GR.
KEGG	cbh:CLC_1253. cbo:CBO1212.
PATRIC	19364509. VBICloBot22612_1198.
Phylogenomic databases
eggNOG	COG3858.
HOGENOM	HBG418928.
OMA	FIMAYDW.
ProtClustDB	CLSK965102.
Family and domain databases
InterPro	IPR011583. Chitinase_II. IPR001223. Glyco_hydro18cat. IPR001579. Glyco_hydro_18_chit_AS. IPR013781. Glyco_hydro_subgr_catalytic. IPR017853. Glycoside_hydrolase_SF. IPR018392. Peptidoglycan-bd_lysin. IPR002482. Peptidoglycan-bd_Lysin_subgr. IPR003646. SH3-like_bac. IPR013247. SH3_3. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 2 hits.
Pfam	PF00704. Glyco_hydro_18. 1 hit. PF01476. LysM. 2 hits. PF08239. SH3_3. 1 hit. [Graphical view]
SMART	SM00636. Glyco_18. 1 hit. SM00257. LysM. 2 hits. SM00287. SH3b. 1 hit. [Graphical view]
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit.
PROSITE	PS01095. CHITINASE_18. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5I148_CLOBH

Accession

Primary (citable) accession number: A5I148
Secondary accession number(s): A7G2V5

Entry history

Integrated into UniProtKB/TrEMBL:	June 26, 2007
Last sequence update:	June 26, 2007
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)