A5GWM1 (A5GWM1_SYNR3) Unreviewed, UniProtKB/TrEMBL
Last modified
May 1, 2013.
Version 43.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Nucleoside diphosphate kinase HAMAP-Rule MF_00451 Short name=NDK HAMAP-Rule MF_00451 Short name=NDP kinase HAMAP-Rule MF_00451 EC=2.7.4.6 HAMAP-Rule MF_00451 Alternative name(s): Nucleoside-2-P kinase HAMAP-Rule MF_00451 | ||||
| Gene names |
| ||||
| Organism | Synechococcus sp. (strain RCC307) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 316278 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechococcus![]() |
Protein attributes
| Sequence length | 187 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate By similarity. HAMAP-Rule MF_00451 |
| Catalytic activity | ATP + nucleoside diphosphate = ADP + nucleoside triphosphate. HAMAP-Rule MF_00451 |
| Cofactor | Magnesium By similarity. HAMAP-Rule MF_00451 |
| Subunit structure | Homotetramer By similarity. HAMAP-Rule MF_00451 |
| Subcellular location | Cytoplasm By similarity HAMAP-Rule MF_00451. |
| Sequence similarities | Belongs to the NDK family. RuleBase RU004011 HAMAP-Rule MF_00451 |
Ontologies
| Keywords | |
|---|---|
| Biological process | Nucleotide metabolism HAMAP-Rule MF_00451 |
| Cellular component | Cytoplasm HAMAP-Rule MF_00451 |
| Ligand | ATP-binding HAMAP-Rule MF_00451 Magnesium HAMAP-Rule MF_00451 Metal-binding HAMAP-Rule MF_00451 Nucleotide-binding |
| Molecular function | Kinase HAMAP-Rule MF_00451 EMBL CAK29280.1 Transferase |
| PTM | Phosphoprotein HAMAP-Rule MF_00451 |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological_process | CTP biosynthetic process Inferred from electronic annotation. Source: HAMAP GTP biosynthetic processInferred from electronic annotation. Source: HAMAP UTP biosynthetic processInferred from electronic annotation. Source: HAMAP |
| Cellular_component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular_function | ATP binding Inferred from electronic annotation. Source: HAMAP metal ion bindingInferred from electronic annotation. Source: UniProtKB-KW nucleoside diphosphate kinase activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Sites | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Active site | 152 | 1 | Pros-phosphohistidine intermediate By similarity HAMAP-Rule MF_00451 | ||||||
| Binding site | 46 | 1 | ATP By similarity HAMAP-Rule MF_00451 | ||||||
| Binding site | 94 | 1 | ATP By similarity HAMAP-Rule MF_00451 | ||||||
| Binding site | 122 | 1 | ATP By similarity HAMAP-Rule MF_00451 | ||||||
| Binding site | 128 | 1 | ATP By similarity HAMAP-Rule MF_00451 | ||||||
| Binding site | 139 | 1 | ATP By similarity HAMAP-Rule MF_00451 | ||||||
| Binding site | 149 | 1 | ATP By similarity HAMAP-Rule MF_00451 | ||||||
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CT978603 Genomic DNA. Translation: CAK29280.1. |
| RefSeq | YP_001228633.1. NC_009482.1. |
3D structure databases | |
| ProteinModelPortal | A5GWM1. |
| SMR | A5GWM1. Positions 39-183. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 316278.SynRCC307_2377. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | CAK29280; CAK29280; SynRCC307_2377. |
| GeneID | 5158124. |
| KEGG | syr:SynRCC307_2377. |
| PATRIC | 23825707. VBISynSp108374_2388. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0105. |
| HOGENOM | HOG000224564. |
| KO | K00940. |
| OMA | IARFERK. |
Family and domain databases | |
| Gene3D | 3.30.70.141. 1 hit. |
| HAMAP | MF_00451. NDP_kinase. |
| InterPro | IPR001564. Nucleoside_diP_kinase. [Graphical view] |
| PANTHER | PTHR11349. PTHR11349. 1 hit. |
| Pfam | PF00334. NDK. 1 hit. [Graphical view] |
| PRINTS | PR01243. NUCDPKINASE. |
| SMART | SM00562. NDK. 1 hit. [Graphical view] |
| SUPFAM | SSF54919. NDK. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | A5GWM1_SYNR3 | ||||||||
| Accession | Primary (citable) accession number: A5GWM1 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

Clusters with
