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A5GWM1 (A5GWM1_SYNR3) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Nucleoside diphosphate kinase HAMAP-Rule MF_00451

Short name=NDK HAMAP-Rule MF_00451
Short name=NDP kinase HAMAP-Rule MF_00451
EC=2.7.4.6 HAMAP-Rule MF_00451
Alternative name(s):
Nucleoside-2-P kinase HAMAP-Rule MF_00451
Gene names
Name:ndk HAMAP-Rule MF_00451 EMBL CAK29280.1
Ordered Locus Names:SynRCC307_2377
OrganismSynechococcus sp. (strain RCC307) [Complete proteome] [HAMAP]
Taxonomic identifier316278 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus

Protein attributes

Sequence length187 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate By similarity. HAMAP-Rule MF_00451

Catalytic activity

ATP + nucleoside diphosphate = ADP + nucleoside triphosphate. HAMAP-Rule MF_00451

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00451

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00451

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00451.

Sequence similarities

Belongs to the NDK family. RuleBase RU004011 HAMAP-Rule MF_00451

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1521Pros-phosphohistidine intermediate By similarity HAMAP-Rule MF_00451
Binding site461ATP By similarity HAMAP-Rule MF_00451
Binding site941ATP By similarity HAMAP-Rule MF_00451
Binding site1221ATP By similarity HAMAP-Rule MF_00451
Binding site1281ATP By similarity HAMAP-Rule MF_00451
Binding site1391ATP By similarity HAMAP-Rule MF_00451
Binding site1491ATP By similarity HAMAP-Rule MF_00451

Sequences

Sequence LengthMass (Da)Tools
A5GWM1 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 37AC508BE7BAE362

FASTA18720,414
        10         20         30         40         50         60 
MKCRKARPSA LPLMWVCLPS GRAATDDGAR LTSQTMSTER TFIAIKPDGV QRGLVGEILG 

        70         80         90        100        110        120 
RFERKGFKLV GLKQLTPSRE LAEQHYGVHK ERPFFAGLVD FITSGPVVAM VWEGDGVIAS 

       130        140        150        160        170        180 
ARKLIGATKP LEAEPGTIRG DLAVNIGRNV IHGSDAAETA QFEIGLWFQP SELNDWTPSD 


QGWRVEG 

« Hide

References

[1]Genoscope
Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RCC307.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CT978603 Genomic DNA. Translation: CAK29280.1.
RefSeqYP_001228633.1. NC_009482.1.

3D structure databases

ProteinModelPortalA5GWM1.
SMRA5GWM1. Positions 39-183.
ModBaseSearch...

Protein-protein interaction databases

STRING316278.SynRCC307_2377.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAK29280; CAK29280; SynRCC307_2377.
GeneID5158124.
KEGGsyr:SynRCC307_2377.
PATRIC23825707. VBISynSp108374_2388.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0105.
HOGENOMHOG000224564.
KOK00940.
OMAIARFERK.

Family and domain databases

Gene3D3.30.70.141. 1 hit.
HAMAPMF_00451. NDP_kinase.
InterProIPR001564. Nucleoside_diP_kinase.
[Graphical view]
PANTHERPTHR11349. PTHR11349. 1 hit.
PfamPF00334. NDK. 1 hit.
[Graphical view]
PRINTSPR01243. NUCDPKINASE.
SMARTSM00562. NDK. 1 hit.
[Graphical view]
SUPFAMSSF54919. NDK. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA5GWM1_SYNR3
AccessionPrimary (citable) accession number: A5GWM1
Entry history
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: May 1, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)