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A5GW85 (SYR_SYNR3) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:SynRCC307_2241
OrganismSynechococcus sp. (strain RCC307) [Complete proteome] [HAMAP]
Taxonomic identifier316278 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus

Protein attributes

Sequence length590 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 590590Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000018137

Regions

Motif131 – 14111"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A5GW85 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 5333C219DC2F833D

FASTA59064,536
        10         20         30         40         50         60 
MLRIAQTLEA QLRAAMQQAF PEADGELNPA LGPASKPEFG DFQANGALAL AKPLKQAPRQ 

        70         80         90        100        110        120 
IAAAIVEQLQ NNPEFSALAE APQIAGPGFI NITLKPSVLA AEVRQRIGDP RLGVAAVEQA 

       130        140        150        160        170        180 
EAPVIVDFSS PNIAKEMHVG HLRSTIIGDC LARVLEFRGH QVLRLNHVGD WGTQFGMLIT 

       190        200        210        220        230        240 
HLKQVAPEAL NTADAIDLGD LVAFYREAKK RFDDDEAFQT TSREEVVKLQ GGDATSLKAW 

       250        260        270        280        290        300 
GLLCDQSRRE FQKIYDRLDI RLNERGESFY NPQLAAVVDD LRSSGLLVTD EGAGCVFLEG 

       310        320        330        340        350        360 
VVGKEGKPLP LIVQKSDGGF NYATTDLAAI RYRLGSAGDG AGRVIYVTDA GQAAHFAGVF 

       370        380        390        400        410        420 
QVAKRAGWVP AAASLEHVPF GLVQGDDGKK LKTRAGDTVR LKDLLDEAVE RAQADLRRRL 

       430        440        450        460        470        480 
EEEERQESES FIDQVATTVG LAAVKYADLS TNRITNYQFS FERMLALTGN TAPYLLYAVV 

       490        500        510        520        530        540 
RISGIARKGG ALDGELPERL VFEEPQEWAL IRQLLQLDAV ISEVESDLLP NRLCTYLFEL 

       550        560        570        580        590 
SQSFNRFYDQ VPVLKADEPM RSSRLALCRL AADTLKLGLS LLGIPSLERM 

« Hide

References

[1]Genoscope
Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RCC307.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CT978603 Genomic DNA. Translation: CAK29144.1.
RefSeqYP_001228497.1. NC_009482.1.

3D structure databases

ProteinModelPortalA5GW85.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING316278.SynRCC307_2241.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAK29144; CAK29144; SynRCC307_2241.
GeneID5157512.
KEGGsyr:SynRCC307_2241.
PATRIC23825437. VBISynSp108374_2255.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMAMEHMGFG.
OrthoDBEOG6JB13C.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_SYNR3
AccessionPrimary (citable) accession number: A5GW85
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 12, 2007
Last modified: May 14, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries