A5GW63 (GLMM_SYNR3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	SynRCC307_2219

Organism

Synechococcus sp. (strain RCC307) [Complete proteome] [HAMAP]

Taxonomic identifier

316278 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	459 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 459	459	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000305686
Sites
	Active site	112	1	Phosphoserine intermediate By similarity
	Metal binding	112	1	Magnesium; via phosphate group By similarity
	Metal binding	249	1	Magnesium By similarity
	Metal binding	251	1	Magnesium By similarity
	Metal binding	253	1	Magnesium By similarity
Amino acid modifications
	Modified residue	112	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A5GW63 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 71A88E77A2994311	FASTA	459	48,384
	10 20 30 40 50 60 MADLASHPVG QPLGGGGVSF GTDGIRGRVG TVMTPALALQ VGYWSGQVLP GDAPVLLGMD 70 80 90 100 110 120 SRSSGPMLVA ALEAGLTAAG REVWTLGLCP TPAVARLVNQ FQAAGGLMVS ASHNPPEDNG 130 140 150 160 170 180 IKLFGPSGAK LSRDQQQAIE AGLRGEVRPA LTSCGPTQRR TELLESYTAL LENSLEGRRL 190 200 210 220 230 240 DGRRIVLDLC WGSATSCAES LFRRLGAEVI ALHSQPDGAA INVGCGSTHL EPLRQAVMEH 250 260 270 280 290 300 GAEMGFAFDG DADRVLAVDG QGRLVDGDHI LYLWGSALAD ADALPQQRLV ATVMSNLGFE 310 320 330 340 350 360 RAWTARGGQL ERTAVGDQHV HAAMAELGAV LGGEQSGHII SADHGMSGDG VLTALQLAAL 370 380 390 400 410 420 LQPGETLSDR VDQSFRSFPQ RLRNVRVPDR DRRKGWQQCD GLTTAIAAAE AAMGDEGRVL 430 440 450 VRASGTEPLL RVMVEASSQE QVDHWTDHLS ELADQLLNV

References

[1]	Genoscope Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RCC307.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT978603 Genomic DNA. Translation: CAK29122.1.
RefSeq	YP_001228475.1. NC_009482.1.
3D structure databases
ProteinModelPortal	A5GW63.
ModBase	Search...
Protein-protein interaction databases
STRING	A5GW63.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5156579.
GenomeReviews	Gene locus SynRCC307_2219 in contig CT978603_GR.
KEGG	syr:SynRCC307_2219.
PATRIC	23825393. VBISynSp108374_2233.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	ESTDNIM.
PhylomeDB	A5GW63.
ProtClustDB	PRK14317.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_SYNR3

Accession

Primary (citable) accession number: A5GW63

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 2, 2007
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program