SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A5GUJ2

- GSA_SYNR3

UniProt

A5GUJ2 - GSA_SYNR3

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Glutamate-1-semialdehyde 2,1-aminomutase
Gene
hemL, SynRCC307_1648
Organism
Synechococcus sp. (strain RCC307)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-4-amino-5-oxopentanoate = 5-aminolevulinate.UniRule annotation

Cofactori

Pyridoxal phosphate By similarity.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. glutamate-1-semialdehyde 2,1-aminomutase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: InterPro
  3. transaminase activity Source: InterPro

GO - Biological processi

  1. chlorophyll biosynthetic process Source: UniProtKB-HAMAP
  2. protoporphyrinogen IX biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Chlorophyll biosynthesis, Porphyrin biosynthesis

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

UniPathwayiUPA00251; UER00317.
UPA00668.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate-1-semialdehyde 2,1-aminomutase (EC:5.4.3.8)
Short name:
GSA
Alternative name(s):
Glutamate-1-semialdehyde aminotransferase
Short name:
GSA-AT
Gene namesi
Name:hemL
Ordered Locus Names:SynRCC307_1648
OrganismiSynechococcus sp. (strain RCC307)
Taxonomic identifieri316278 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus
ProteomesiUP000001115: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 434434Glutamate-1-semialdehyde 2,1-aminomutaseUniRule annotation
PRO_0000382386Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei273 – 2731N6-(pyridoxal phosphate)lysine By similarity

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi316278.SynRCC307_1648.

Structurei

3D structure databases

ProteinModelPortaliA5GUJ2.
SMRiA5GUJ2. Positions 7-427.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0001.
HOGENOMiHOG000020210.
KOiK01845.
OMAiRAIKPYP.
OrthoDBiEOG6QVRHN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPiMF_00375. HemL_aminotrans_3.
InterProiIPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00713. hemL. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A5GUJ2-1 [UniParc]FASTAAdd to Basket

« Hide

MVTAAALNTS RSDALFTAAQ QLMPGGVNSP VRAFRSVGGQ PIVFDRVEGA    50
YAWDVDGNRY IDYIGSWGPA ICGHANPEVI EALQQALTKG TSFGAPCALE 100
NTLAEMVINA VPSVEMVRFV NSGTEACMAV LRLMRAYTGR EKVIKFEGCY 150
HGHADMFLVK AGSGVATLGL PDSPGVPSST TANTLTAPYN DLEAVKALFA 200
ENPDSISGVI LEPVVGNAGF IPPDFGFLEG LREITREYGA LLVFDEVMTG 250
FRISYGGAQA RFGITPDLTT MGKVIGGGLP VGAYGGRKDI MEMVAPAGPM 300
YQAGTLSGNP LAMTAGIKTL ELLKRPGTYE KLEATTKRLA EGIQEAAKAA 350
GLPVCGNSIS AMFGFFLCDG PVRNFEEAKA NDSERFAKLH RAMLERGVYL 400
APSSFEAGFT SLAHSDADID ATLEAFRESF QLIA 434
Length:434
Mass (Da):45,953
Last modified:June 12, 2007 - v1
Checksum:i0D55E63001E0A615
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT978603 Genomic DNA. Translation: CAK28551.1.
RefSeqiWP_011936065.1. NC_009482.1.
YP_001227904.1. NC_009482.1.

Genome annotation databases

EnsemblBacteriaiCAK28551; CAK28551; SynRCC307_1648.
GeneIDi5157555.
KEGGisyr:SynRCC307_1648.
PATRICi23824217. VBISynSp108374_1658.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT978603 Genomic DNA. Translation: CAK28551.1 .
RefSeqi WP_011936065.1. NC_009482.1.
YP_001227904.1. NC_009482.1.

3D structure databases

ProteinModelPortali A5GUJ2.
SMRi A5GUJ2. Positions 7-427.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 316278.SynRCC307_1648.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAK28551 ; CAK28551 ; SynRCC307_1648 .
GeneIDi 5157555.
KEGGi syr:SynRCC307_1648.
PATRICi 23824217. VBISynSp108374_1658.

Phylogenomic databases

eggNOGi COG0001.
HOGENOMi HOG000020210.
KOi K01845.
OMAi RAIKPYP.
OrthoDBi EOG6QVRHN.

Enzyme and pathway databases

UniPathwayi UPA00251 ; UER00317 .
UPA00668 .

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPi MF_00375. HemL_aminotrans_3.
InterProi IPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view ]
PANTHERi PTHR11986. PTHR11986. 1 hit.
Pfami PF00202. Aminotran_3. 1 hit.
[Graphical view ]
PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMi SSF53383. SSF53383. 1 hit.
TIGRFAMsi TIGR00713. hemL. 1 hit.
PROSITEi PS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Genoscope
    Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RCC307.

Entry informationi

Entry nameiGSA_SYNR3
AccessioniPrimary (citable) accession number: A5GUJ2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 1, 2009
Last sequence update: June 12, 2007
Last modified: September 3, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi