Skip Header

Contribute Send feedback
Read comments (?) or add your own

A5GUC8 (A5GUC8_SYNR3) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha HAMAP MF_00823
Short name=ACCase subunit alpha HAMAP MF_00823
Short name=Acetyl-CoA carboxylase carboxyltransferase subunit alpha HAMAP MF_00823
EC=6.4.1.2 HAMAP MF_00823
Gene names
Name:accA HAMAP MF_00823 EMBL CAK28487.1
Ordered Locus Names:SynRCC307_1584
OrganismSynechococcus sp. (strain RCC307) [Complete proteome] [HAMAP]
Taxonomic identifier316278 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length339 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA By similarity. HAMAP MF_00823 SAAS SAAS011763

Catalytic activity

ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA. HAMAP MF_00823 SAAS SAAS011763

Pathway

Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1. HAMAP MF_00823 SAAS SAAS011763

Subunit structure

Acetyl-CoA carboxylase is an heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD) By similarity. HAMAP MF_00823 SAAS SAAS011763

Subcellular location

Cytoplasm By similarity HAMAP MF_00823 SAAS SAAS011763.

Sequence similarities

Belongs to the AccA family. HAMAP MF_00823

Sequences

Sequence LengthMass (Da)Tools
A5GUC8 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: E4AFA6FD90AB8BB2

FASTA33937,088
        10         20         30         40         50         60 
MAPRRLLLDF EKPLVDLEEQ IEQIRQLARD SEVDVSQQLL QLETLATRRR EEIFSSLTPA 

        70         80         90        100        110        120 
QKIQVARHPQ RPSCLDYIQL LSDDWIELHG DRSGSDDQAL VGGLGRLDGR AVLFIGHQKG 

       130        140        150        160        170        180 
RDTKENVARN FGMASPGGYR KALRLMQHAS RFQLPVISFI DTPGAYAGLK AEELGQGEAI 

       190        200        210        220        230        240 
AVNLREMFAL EVPVIATVIG EGGSGGALGI GVADRLMMFE HSVYTVASPE ACASILWRDA 

       250        260        270        280        290        300 
AKASTAAEAL KITARDLSQL GIVDRVLGEP SGGNHWAPLQ AADTLRTALC EELNQLASLS 

       310        320        330 
GQELRDQRYS KYRRIGRYLE HPEMEAAATS DTLESSASA

« Hide

References

[1]Genoscope
Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CT978603 Genomic DNA. Translation: CAK28487.1.
RefSeqYP_001227840.1. NC_009482.1.

3D structure databases

ProteinModelPortalA5GUC8.
SMRA5GUC8. Positions 7-317.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5GUC8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5158767.
GenomeReviewsGene locus SynRCC307_1584 in contig CT978603_GR.
KEGGsyr:SynRCC307_1584.
PATRIC23824097. VBISynSp108374_1598.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0825.
HOGENOMHBG286557.
OMAGRDTKDN.
PhylomeDBA5GUC8.
ProtClustDBPRK05724.

Family and domain databases

HAMAPMF_00823. AcetylCoA_CT_alpha.
[Tree]
InterProIPR001095. Acetyl_CoA_COase_a_su.
IPR011763. COA_CT_C.
[Graphical view]
KOK01962.
PANTHERPTHR22855:SF3. Ac-CoA_carboxylA. 1 hit.
PfamPF03255. ACCA. 1 hit.
[Graphical view]
PRINTSPR01069. ACCCTRFRASEA.
TIGRFAMsTIGR00513. AccA. 1 hit.
PROSITEPS50989. COA_CT_CTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5GUC8_SYNR3
AccessionPrimary (citable) accession number: A5GUC8
Entry history
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info