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Protein

Glutamate decarboxylase

Gene

gadA

Organism
Synechococcus sp. (strain RCC307)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:gadAImported
Ordered Locus Names:SynRCC307_1544Imported
OrganismiSynechococcus sp. (strain RCC307)Imported
Taxonomic identifieri316278 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus
ProteomesiUP000001115: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi316278.SynRCC307_1544.

Structurei

3D structure databases

ProteinModelPortaliA5GU88.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiHINRVAT.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

A5GU88-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
METSRPGLDL ETNLGHRLQQ RNHTDAVLPR DQLAKHGLHA DLAYQLIHDH
60 70 80 90 100
LMLDGNAMLN LATFVGTWME PEALHLMREC ADKNMIDKDE YPQTAELENR
110 120 130 140 150
CLRMLARLWN APDPEAAVGT STTGSSEACM LGGMVLRWHW RQRRAAQGLD
160 170 180 190 200
DRRPNLVMGT NTQICWDKFC AYFDVEARMV PISRDHLQMT AEGAVAACDE
210 220 230 240 250
NTIGVVGVLG STFDGSYEPI EAIQQGLDQL QERTGLDIPI HVDGASGAFV
260 270 280 290 300
APFNSPELPW DFRLPRVKSI NTSGHKYGGV LPGVGWVLWR EQADLPEELR
310 320 330 340 350
FNVNYLGGQM PTIGMNFSRP GAQVVAQYFN FIHLGHAGYC QRMACLEATA
360 370 380 390 400
SYLADSIAAM APMKLLSHPR GQLPVFAVTL EDSVDTWTVF QLSERLRARG
410 420 430 440 450
WQVPAYTMPA ACEDLAVLRF VIRAGFTRDM ADLLLRDLQN AVDWFQQLSS
460
PMPDPNPEHR PFHH
Length:464
Mass (Da):51,943
Last modified:June 12, 2007 - v1
Checksum:i6EDED4C0D2D802FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT978603 Genomic DNA. Translation: CAK28447.1.
RefSeqiWP_011935961.1. NC_009482.1.
YP_001227800.1. NC_009482.1.

Genome annotation databases

EnsemblBacteriaiCAK28447; CAK28447; SynRCC307_1544.
GeneIDi5157958.
KEGGisyr:SynRCC307_1544.
PATRICi23824015. VBISynSp108374_1557.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT978603 Genomic DNA. Translation: CAK28447.1.
RefSeqiWP_011935961.1. NC_009482.1.
YP_001227800.1. NC_009482.1.

3D structure databases

ProteinModelPortaliA5GU88.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi316278.SynRCC307_1544.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAK28447; CAK28447; SynRCC307_1544.
GeneIDi5157958.
KEGGisyr:SynRCC307_1544.
PATRICi23824015. VBISynSp108374_1557.

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiHINRVAT.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Genoscope
    Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RCC307Imported.

Entry informationi

Entry nameiA5GU88_SYNR3
AccessioniPrimary (citable) accession number: A5GU88
Entry historyi
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: February 4, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.