A5GTP7 (A5GTP7_SYNR3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
N-acetyl-gamma-glutamyl-phosphate reductase HAMAP MF_00150
Short name=AGPR HAMAP MF_00150
EC=1.2.1.38 HAMAP MF_00150

Alternative name(s):
N-acetyl-glutamate semialdehyde dehydrogenase HAMAP MF_00150

Gene names

Name:	argC HAMAP MF_00150 EMBL CAK28256.1
Ordered Locus Names:	SynRCC307_1353

Organism

Synechococcus sp. (strain RCC307) [Complete proteome] [HAMAP]

Taxonomic identifier

316278 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	363 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH. HAMAP MF_00150 SAAS SAAS023013
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate. RuleBase RU004258 Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4. HAMAP MF_00150 SAAS SAAS023013
Subcellular location	Cytoplasm By similarity HAMAP MF_00150 SAAS SAAS023013.
Sequence similarities	Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. HAMAP MF_00150

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis HAMAP MF_00150 SAAS SAAS023013
Cellular component	Cytoplasm HAMAP MF_00150 SAAS SAAS023013
Ligand	NADP HAMAP MF_00150 SAAS SAAS023013
Molecular function	Oxidoreductase HAMAP MF_00150 SAAS SAAS023013 EMBL CAK28256.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	N-acetyl-gamma-glutamyl-phosphate reductase activity Inferred from electronic annotation. Source: HAMAP NAD binding Inferred from electronic annotation. Source: InterPro protein dimerization activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	166	1	By similarity HAMAP MF_00150

Sequences

	Sequence		Length	Mass (Da)
	A5GTP7 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 83B0315D228BDFF7	FASTA	363	38,828
	10 20 30 40 50 60 MQPVRPVAPT SFKRIAVIGA SGYGGLQTLR LLQDHPHFEV TFLGGERSAG KRWSELTPFL 70 80 90 100 110 120 PLGDDLVVQS PDADAIAAAA DAAVFSLPNG LASQLAPKLL QRGVRVVDLS ADYRFPSLSQ 130 140 150 160 170 180 WSATYRQEAA AQQRQDDALC QQAVYGLVEW AGDALAEAKL VGAPGCFPTA SLLALMPLLQ 190 200 210 220 230 240 QGLIEGEGIV IDAKTGTSGG GRAAKEHLLL AEAAESVSPY GVVGHRHTAE IELLASRAAG 250 260 270 280 290 300 RPIQLQFTPH LMPMVRGLLA TVYGRLRDPG LTAEDLTTVY QVTYRDHPCV EVLPVGTYPA 310 320 330 340 350 360 TKWVRQTNRA VLSVAVDQRT RQVIVMSAID NLLKGQAGQA VQCLNVMAGL PQQTGLPLLP FYP

References

[1]	Genoscope Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT978603 Genomic DNA. Translation: CAK28256.1.
RefSeq	YP_001227609.1. NC_009482.1.
3D structure databases
ProteinModelPortal	A5GTP7.
ModBase	Search...
Protein-protein interaction databases
STRING	A5GTP7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5157320.
GenomeReviews	Gene locus SynRCC307_1353 in contig CT978603_GR.
KEGG	syr:SynRCC307_1353.
PATRIC	23823603. VBISynSp108374_1354.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0002.
HOGENOM	HBG294213.
OMA	TAEDCTT.
PhylomeDB	A5GTP7.
ProtClustDB	PRK00436.
Family and domain databases
HAMAP	MF_00150. ArgC_type1. [Tree]
InterPro	IPR023013. AGPR_AS. IPR000706. AGPR_type-1. IPR016040. NAD(P)-bd_dom. IPR000534. Semialdehyde_DH_NAD-bd. IPR012280. Semialdhyde_DH_dimer_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00145.
Pfam	PF01118. Semialdhyde_dh. 1 hit. PF02774. Semialdhyde_dhC. 1 hit. [Graphical view]
SMART	SM00859. Semialdhyde_dh. 1 hit. [Graphical view]
TIGRFAMs	TIGR01850. ArgC. 1 hit.
PROSITE	PS01224. ARGC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A5GTP7_SYNR3

Accession

Primary (citable) accession number: A5GTP7

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)