A5GTE9 (FBSB_SYNR3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase
Short name=FBPase class 2/SBPase
EC=3.1.3.11
EC=3.1.3.37

Gene names

Ordered Locus Names:

SynRCC307_1255

Organism

Synechococcus sp. (strain RCC307) [Complete proteome] [HAMAP]

Taxonomic identifier

316278 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	334 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate, respectively By similarity.
Catalytic activity	D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. Sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate.
Cofactor	Manganese By similarity.
Pathway	Carbohydrate biosynthesis; Calvin cycle.
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the FBPase class 2 family.

Ontologies

Keywords
Biological process	Calvin cycle Carbohydrate metabolism
Ligand	Manganese Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycerol metabolic process Inferred from electronic annotation. Source: InterPro reductive pentose-phosphate cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	fructose 1,6-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW sedoheptulose-bisphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 334	334	D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase		PRO_0000342733
Regions
	Region	88 – 90	3	Substrate binding By similarity
	Region	164 – 166	3	Substrate binding By similarity
	Region	186 – 188	3	Substrate binding By similarity
Sites
	Metal binding	33	1	Manganese 1 By similarity
	Metal binding	57	1	Manganese 1 By similarity
	Metal binding	85	1	Manganese 2 By similarity
	Metal binding	88	1	Manganese 2 By similarity
	Metal binding	213	1	Manganese 2 By similarity
	Binding site	119	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	A5GTE9 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 49563B2767E2FBED	FASTA	334	34,810
	10 20 30 40 50 60 MDRTLIQEIL EVVEQAAIAS AKLTGCGLKN EADAAAVEAM RDRMGKINMR GRIVIGEGER 70 80 90 100 110 120 DEAPMLYIGE EVGSGTGPGV DFAVDPCEGT NLCANSQRGS MAVLAASETG GLFNAPDFYM 130 140 150 160 170 180 KKLAAPPAAK GKVDINKSAT ENINILSECL GIAVSDLVIV VMDRARHKDL IAEIRATGAR 190 200 210 220 230 240 VQPISDGDVQ AAIACGFAGT GTHCLMGIGA APEGVISAAA LRALGGHFQG QLVYDPAVAQ 250 260 270 280 290 300 TKEWEGLTRE GNLARLAEMG ISDPDKVYEA NELASGENVV FAGSGITDGL LFGGVKFESD 310 320 330 CVRTSSLVIS TLDNSARFTD TVHIKPGAQS IALR

References

[1]	Genoscope Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RCC307.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT978603 Genomic DNA. Translation: CAK28158.1.
RefSeq	YP_001227511.1. NC_009482.1.
3D structure databases
ProteinModelPortal	A5GTE9.
ModBase	Search...
Protein-protein interaction databases
STRING	A5GTE9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5157397.
GenomeReviews	Gene locus SynRCC307_1255 in contig CT978603_GR.
KEGG	syr:SynRCC307_1255.
PATRIC	23823405. VBISynSp108374_1256.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1494.
HOGENOM	HBG284837.
OMA	MYDPSAV.
PhylomeDB	A5GTE9.
ProtClustDB	PRK09479.
Family and domain databases
InterPro	IPR004464. FBPase_class-2/SBPase. [Graphical view]
KO	K11532.
Pfam	PF03320. FBPase_glpX. 1 hit. [Graphical view]
PIRSF	PIRSF004532. GlpX. 1 hit.
TIGRFAMs	TIGR00330. GlpX. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FBSB_SYNR3

Accession

Primary (citable) accession number: A5GTE9

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 2008
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program