A5GT49 (COMB_SYNR3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable 2-phosphosulfolactate phosphatase
EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	SynRCC307_1155

Organism

Synechococcus sp. (strain RCC307) [Complete proteome] [HAMAP]

Taxonomic identifier

316278 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	245 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity. HAMAP MF_00490
Sequence similarities	Belongs to the ComB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 245	245	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_1000014472

Sequences

	Sequence		Length	Mass (Da)
	A5GT49 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 786C9638D37E4161	FASTA	245	26,118
	10 20 30 40 50 60 MRLSYFHSPD RVPAEGMADA AVAIDVLRAT TTMAWALHNG AEAIQAFADL AQLDAAASAW 70 80 90 100 110 120 PDDQSLRAGE RGGQKLEGFD LGNSPLAVTP ERIGGRRIFM STTNGTRALD RVRSAPMLLT 130 140 150 160 170 180 AALVNRSAVA QRLLQHRPEQ IWMVGSGWEG AYSLEDSLAA GALADALLEG SGASLLDLAG 190 200 210 220 230 240 NDETCAAHAL WQQWKDQPEA LLRLASHGQR LQRLGDHDAD LACCATVDSL TVVPSQDEPG VLRLS

References

[1]	Genoscope Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RCC307.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT978603 Genomic DNA. Translation: CAK28058.1.
RefSeq	YP_001227411.1. NC_009482.1.
3D structure databases
ProteinModelPortal	A5GT49.
ModBase	Search...
Protein-protein interaction databases
STRING	A5GT49.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5156517.
GenomeReviews	Gene locus SynRCC307_1155 in contig CT978603_GR.
KEGG	syr:SynRCC307_1155.
PATRIC	23823209. VBISynSp108374_1159.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2045.
HOGENOM	HBG633644.
OMA	GWEGAYS.
PhylomeDB	A5GT49.
Family and domain databases
HAMAP	MF_00490. ComB. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. IPR022995. Pase_ComB. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
KO	K05979.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
SUPFAM	SSF142823. SSF142823. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_SYNR3

Accession

Primary (citable) accession number: A5GT49

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program