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A5GRY6 (A5GRY6_SYNR3) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA gyrase subunit A HAMAP MF_01897
EC=5.99.1.3 HAMAP MF_01897
Gene names
Name:gyrA HAMAP MF_01897 EMBL CAK27645.1
Ordered Locus Names:SynRCC307_0742
OrganismSynechococcus sp. (strain RCC307) [Complete proteome] [HAMAP]
Taxonomic identifier316278 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length859 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings By similarity. SAAS SAAS006691 HAMAP MF_01897

Catalytic activity

ATP-dependent breakage, passage and rejoining of double-stranded DNA. SAAS SAAS006691 HAMAP MF_01897

Subunit structure

Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis. The enzyme forms an A2B2 tetramer By similarity. HAMAP MF_01897

Subcellular location

Cytoplasm By similarity SAAS SAAS006691 HAMAP MF_01897.

Sequence similarities

Belongs to the topoisomerase GyrA/ParC subunit family. HAMAP MF_01897

Sequences

Sequence LengthMass (Da)Tools
A5GRY6 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 517E7D10F130381D

FASTA85994,635
        10         20         30         40         50         60 
MADPTGAGNP SERIIQTDLR NEMSRSYLEY AMSVIVGRAL PDARDGLKPV HRRILYAMYE 

        70         80         90        100        110        120 
LGLTAERPYR KCARVVGEVL GKYHPHGDTA VYDALVRMAQ NFSMRAPLID GHGNFGSVDN 

       130        140        150        160        170        180 
DPPAAMRYTE SRLQSLTTDS LLEDIESETV DFIDNFDGSQ QEPTVLPARV PQLLLNGSAG 

       190        200        210        220        230        240 
IAVGMATNIP PHNLGELIDG VLALIADPQI EERQLMSIIP GPDFPTGGQI LGRKGIRETY 

       250        260        270        280        290        300 
TGGRGSITMR GVAAIETIEA KGRPDRDAVI ITELPYQTNK ASLIERIAEL VNDKKLEGIA 

       310        320        330        340        350        360 
DIRDESDRDG MRIVIELRRD AYPQVVLNNL YKLTPLQNNF SAYTLALVKG EPVVLNLKRM 

       370        380        390        400        410        420 
LEVFLDFRIE TIERRTKYLL RKAEERDHIL QGLLVALNDL DAIIQLIRNA ADAATARQGL 

       430        440        450        460        470        480 
VNDHGLSEIQ ADAILQMQLR RLTALEADKI RLEHEDLIAK IADYKDILQR RERVLSIIEE 

       490        500        510        520        530        540 
ELRQLKERHN TPRRTEILDL EGGLEDIDLI ANERSVVLLT ENGYLKRMPV SEFESTSRGT 

       550        560        570        580        590        600 
RGKAGTKSQG EEAVRLFISC NDHDSLLLFS DRGVVYSLPA YRVPIASRAA KGTPVVQLLP 

       610        620        630        640        650        660 
IPREEQITSL LAVSAFEEDV QLVMLTTGGF IKRTPLSAFS NIRANGLIAI NLEDADSLRW 

       670        680        690        700        710        720 
VRLARAGDSV LIGSINGMTI HFRINDQDLR PLGRTARGVR AMALRDGDSL VSMDVLPAEL 

       730        740        750        760        770        780 
ADRIAAAGEA SDGESEEAAS SDGPWVLVAT ASGLGKRVPV DQFRLQRRAG LGLRGIKFRR 

       790        800        810        820        830        840 
DGDALVGLCV MGAEEELLLV SERGVIVRLQ SDVIPQQSRA ATGVRLQRLD KGDRLAEVVL 

       850 
VPPEAETDDE SAEAAEAEA

« Hide

References

[1]Genoscope
Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CT978603 Genomic DNA. Translation: CAK27645.1.
RefSeqYP_001226998.1. NC_009482.1.

3D structure databases

ProteinModelPortalA5GRY6.
SMRA5GRY6. Positions 36-497.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5GRY6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5157763.
GenomeReviewsGene locus SynRCC307_0742 in contig CT978603_GR.
KEGGsyr:SynRCC307_0742.
PATRIC23822350. VBISynSp108374_0733.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0188.
HOGENOMHBG635183.
OMATSIPPHR.
PhylomeDBA5GRY6.
ProtClustDBPRK05560.

Family and domain databases

HAMAPMF_01897. GyrA.
[Tree]
InterProIPR005743. GyrA.
IPR006691. GyrA/parC_pinwhl.
IPR002205. Topo_IIA_A/C.
IPR013758. Topo_IIA_A/C_ab.
IPR013757. Topo_IIA_A_a.
IPR013760. Topo_IIA_cen.
[Graphical view]
Gene3DG3DSA:3.90.199.10. Topo_IIA_A/C_ab. 1 hit.
G3DSA:1.10.268.10. Topo_IIA_A_a. 1 hit.
KOK02469.
PfamPF03989. DNA_gyraseA_C. 6 hits.
PF00521. DNA_topoisoIV. 1 hit.
[Graphical view]
SMARTSM00434. TOP4c. 1 hit.
[Graphical view]
SUPFAMSSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMsTIGR01063. GyrA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA5GRY6_SYNR3
AccessionPrimary (citable) accession number: A5GRY6
Entry history
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info