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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Synechococcus sp. (strain RCC307)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Tricarboxylic acid cycle

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:SynRCC307_0549
OrganismiSynechococcus sp. (strain RCC307)
Taxonomic identifieri316278 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesSynechococcaceaeSynechococcus
Proteomesi
  • UP000001115 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003255151 – 477Probable malate:quinone oxidoreductaseAdd BLAST477

Interactioni

Protein-protein interaction databases

STRINGi316278.SynRCC307_0549.

Structurei

3D structure databases

ProteinModelPortaliA5GRE3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OMAiEPIAATK.
OrthoDBiPOG091H0B7C.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.

Sequencei

Sequence statusi: Complete.

A5GRE3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDRYDAVLV GAGIMGATLA ALLHELDPAM RLLMLERLDG PALESSAAAN
60 70 80 90 100
NAGTGHAANC ELNYTPQQAD GSVATAKALA INAAFERSLE FWATLRERGE
110 120 130 140 150
LDTPAFLNSV PHISFVWGQG DVAFLRQRHQ QLSALPAFAG MEWSSDPAEL
160 170 180 190 200
AEWMPLVMQG RGASEPVAAT RISRGTDVDF GSLTRLYLQD LQRSGALELR
210 220 230 240 250
TGCEVNDLTR KSNGDWSVEL AGGERVQTPF VFLGAGGGAL PLLQRSTIPE
260 270 280 290 300
AKAFAGFPVS GQWLVCGDNQ LASRHLAKVY GKAKVGAPPM SVPHLDTRFI
310 320 330 340 350
NGERSLLFGP FAGFSTKFLK QGSLLDLPRS VRIGNLLPML QVGAGNFPLV
360 370 380 390 400
QYLINQLRQS PEQRLEALQQ FLPQAEASDW TLSVAGQRVQ IIKNGPKGGQ
410 420 430 440 450
LQLGTEVVAA ADGSLAALLG ASPGASTAVT TMLEVLERCF ASRLATPAWQ
460 470
ERLKALFPSW GGDVLSSRSR NTAVLGL
Length:477
Mass (Da):50,985
Last modified:June 12, 2007 - v1
Checksum:i8710737E2C97F3A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT978603 Genomic DNA. Translation: CAK27452.1.
RefSeqiWP_011934967.1. NC_009482.1.

Genome annotation databases

EnsemblBacteriaiCAK27452; CAK27452; SynRCC307_0549.
KEGGisyr:SynRCC307_0549.
PATRICi23821958. VBISynSp108374_0542.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT978603 Genomic DNA. Translation: CAK27452.1.
RefSeqiWP_011934967.1. NC_009482.1.

3D structure databases

ProteinModelPortaliA5GRE3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi316278.SynRCC307_0549.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAK27452; CAK27452; SynRCC307_0549.
KEGGisyr:SynRCC307_0549.
PATRICi23821958. VBISynSp108374_0542.

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OMAiEPIAATK.
OrthoDBiPOG091H0B7C.

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMQO_SYNR3
AccessioniPrimary (citable) accession number: A5GRE3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: June 12, 2007
Last modified: November 2, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.