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A5GQQ0 (UPPP_SYNR3) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:SynRCC307_0306
OrganismSynechococcus sp. (strain RCC307) [Complete proteome] [HAMAP]
Taxonomic identifier316278 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus

Protein attributes

Sequence length286 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 286286Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000303037

Regions

Transmembrane17 – 3721Helical; Potential
Transmembrane49 – 6921Helical; Potential
Transmembrane98 – 11821Helical; Potential
Transmembrane126 – 14621Helical; Potential
Transmembrane159 – 17921Helical; Potential
Transmembrane204 – 22421Helical; Potential
Transmembrane232 – 25221Helical; Potential
Transmembrane261 – 28121Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
A5GQQ0 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: C638DC3B49329606

FASTA28629,970
        10         20         30         40         50         60 
MDAAAELTLL EACWRTVVLG IVQGLTEFLP ISSTAHLKVV PVLAGWGDPG VAVTAVIQLG 

        70         80         90        100        110        120 
SIAAVIGYFR SDLLQVCRGL ARALREGDWG SPDARLGIAI AVGTLPVVVA GLLIKLFWPG 

       130        140        150        160        170        180 
YETSPLRSVA SIGIVSIVMA LLLALAERLG QRRKQLPSVQ GLDGVVVGLA QALAIIPGVS 

       190        200        210        220        230        240 
RSGSTLTASL LFGWQRSDAA RFSFLLGIPA ITLAGLVELK GAFAEGSVYG PLPMLLGILS 

       250        260        270        280 
AAVVSWLAIA WLLKFLQTNS TWPFVIYRLV FGVVLLALVL ANPTLG 

« Hide

References

[1]Genoscope
Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RCC307.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CT978603 Genomic DNA. Translation: CAK27209.1.
RefSeqYP_001226562.1. NC_009482.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING316278.SynRCC307_0306.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAK27209; CAK27209; SynRCC307_0306.
GeneID5158866.
KEGGsyr:SynRCC307_0306.
PATRIC23821440. VBISynSp108374_0294.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMAAQCFALI.
OrthoDBEOG6QP13M.
ProtClustDBPRK00281.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_SYNR3
AccessionPrimary (citable) accession number: A5GQQ0
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: June 12, 2007
Last modified: February 19, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families