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A5GPF0 (A5GPF0_SYNPW) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Biosynthetic arginine decarboxylase HAMAP MF_01417
Short name=ADC HAMAP MF_01417
EC=4.1.1.19 HAMAP MF_01417
Gene names
Name:speA HAMAP MF_01417 EMBL CAK24815.1
Ordered Locus Names:SynWH7803_2389
OrganismSynechococcus sp. (strain WH7803) [Complete proteome] [HAMAP]
Taxonomic identifier32051 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length636 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the biosynthesis of agmatine from arginine By similarity. HAMAP MF_01417 SAAS SAAS009006

Catalytic activity

L-arginine = agmatine + CO2. HAMAP MF_01417 SAAS SAAS009006 RuleBase RU003740

Cofactor

Magnesium By similarity. HAMAP MF_01417 SAAS SAAS009006 RuleBase RU003740

Pyridoxal phosphate By similarity. HAMAP MF_01417 SAAS SAAS000183

Pathway

Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1. HAMAP MF_01417

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily. HAMAP MF_01417

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region288 – 29811Substrate-binding By similarity HAMAP MF_01417

Amino acid modifications

Modified residue1061N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01417

Sequences

Sequence LengthMass (Da)Tools
A5GPF0 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 216147F6BAEB4B31

FASTA63669,842
        10         20         30         40         50         60 
MAHTSTAGPW TVQDGADLYG LDRWGDPYFS TNSRGHITVQ PQGERGGSID LIELVEGLQA 

        70         80         90        100        110        120 
RDLGLPLLIR FDDILEDRLE RLHAAFDRAI AHYGYAGRYQ GVFPVKCNQQ RHVVERIVES 

       130        140        150        160        170        180 
GQRWHFGLEA GSKAELLIAL SLLNDPDALL ICNGYKDQRY LETAILARKL GRQPVVVIEQ 

       190        200        210        220        230        240 
PDEVERIIRA SDHLGAAPMI GIRARLSTRS TGRWGSSVGD RAKFGLSIPE LLDTTEALRN 

       250        260        270        280        290        300 
AGLLKELRLL HFHIGSQIND IAVLKDALQE AGQIYGELHR LGAPMGFLDV GGGLGVDYDG 

       310        320        330        340        350        360 
SRSATAASTN YSLQNYANDV VATVKECCEP SGVPVPTLVS ESGRALASHF SVLVFDILGT 

       370        380        390        400        410        420 
GAAPDERPEP MDDDPLILRN LHETFDGITT ANLQEAWNDV LKFKGDALSA FRLGYLSLPE 

       430        440        450        460        470        480 
RARAEQLAWA CARRISRLLP ADDSSPEELR NLRASLASTY YGNFSVFRSA PDTWAIDQLF 

       490        500        510        520        530        540 
PVMPIHRLDE QPNQLGSIAD LTCDSDGKLA RFIQGGQSKP LLELHSPKPD QPYLIGLFLA 

       550        560        570        580        590        600 
GAYQEVMGNL HNLFGSTNAV HIRLAPGGGY LLDHVVRGDT NSDVLEAMEH DPDLMLERLR 

       610        620        630 
LASEEAIREQ RLSVNDARLL ISHVASSLQQ ATYLQG

« Hide

References

[1]Genoscope
Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CT971583 Genomic DNA. Translation: CAK24815.1.
RefSeqYP_001226112.1. NC_009481.1.

3D structure databases

ProteinModelPortalA5GPF0.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5GPF0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5146211.
GenomeReviewsGene locus SynWH7803_2389 in contig CT971583_GR.
KEGGsyx:SynWH7803_2389.
PATRIC23831060. VBISynSp43824_2467.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1166.
HOGENOMHBG321436.
OMALICNGYK.
PhylomeDBA5GPF0.
ProtClustDBPRK05354.

Enzyme and pathway databases

BioCycSSP32051:SYNWH7803_2389-MONOMER.

Family and domain databases

HAMAPMF_01417. SpeA.
[Tree]
InterProIPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022657. De-COase2_CS.
IPR022644. De-COase2_N.
IPR022653. De-COase2_pyr-phos_BS.
IPR000183. Orn/DAP/Arg_de-COase.
[Graphical view]
Gene3DG3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 2 hits.
KOK01585.
PANTHERPTHR11482:SF3. Arg_decrbxlase. 1 hit.
PfamPF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view]
PIRSFPIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSPR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR01273. SpeA. 1 hit.
PROSITEPS00878. ODR_DC_2_1. 1 hit.
PS00879. ODR_DC_2_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5GPF0_SYNPW
AccessionPrimary (citable) accession number: A5GPF0
Entry history
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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