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A5GP97 (SYR_SYNPW) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:SynWH7803_2336
OrganismSynechococcus sp. (strain WH7803) [Complete proteome] [HAMAP]
Taxonomic identifier32051 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus

Protein attributes

Sequence length597 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 597597Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000018136

Regions

Motif137 – 14711"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A5GP97 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 03AE91C0B7BFA57B

FASTA59765,718
        10         20         30         40         50         60 
MLRIAHRLDL QLRAAMDRAF PEQAAAARQA SQPLDPQLAP ASKPEFGDFQ ANGALALAKP 

        70         80         90        100        110        120 
LKQAPRQIAT AIVAQLQADP AFTDLCLEPQ IAGPGFINLT VRPERLAAEV SARLGDQRLG 

       130        140        150        160        170        180 
VPAVEQAAPV VVDFSSPNIA KEMHVGHLRS TIIGDSLARV LEFRGHPVLR LNHVGDWGTQ 

       190        200        210        220        230        240 
FGMLITHLKQ VAPDALDTAD AVDLGDLVAF YREAKKRFDD DEAFQTTSRE EVVKLQGGDP 

       250        260        270        280        290        300 
VSLKAWGLLC DQSRREFQKI YDRLDIRLNE RGESFYNPFL PAVIDGLKDA ELLVTDDGAQ 

       310        320        330        340        350        360 
CVFLEGVQGK DGKPLPVIVQ KSDGGFNYAT TDLAAIRYRF GAAPDGDDAR RVIYVTDAGQ 

       370        380        390        400        410        420 
ANHFAGVFQV AQRAGWIPEG ARLEHVPFGL VQGEDGKKLK TRAGDTVRLR DLLDEAVERA 

       430        440        450        460        470        480 
ETDLRSRLNE EERSESEEFI QHVAGTVGLA AVKYADLSQN RITNYQFSFD RMLALQGNTA 

       490        500        510        520        530        540 
PYLLYAVVRI AGIARKGGDL EVLTGQLQFS EPQEWALVRE LLKFDAVIAE VEEELLPNRL 

       550        560        570        580        590 
CSYLFELSQV FNRFYDQVPV LKADAEALPS RLALCRLTAD TLKSGLGLLG IPTLDRM 

« Hide

References

[1]Genoscope
Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: WH7803.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CT971583 Genomic DNA. Translation: CAK24762.1.
RefSeqYP_001226059.1. NC_009481.1.

3D structure databases

ProteinModelPortalA5GP97.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING32051.SynWH7803_2336.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAK24762; CAK24762; SynWH7803_2336.
GeneID5147434.
KEGGsyx:SynWH7803_2336.
PATRIC23830950. VBISynSp43824_2412.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMADGTAVYM.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_SYNPW
AccessionPrimary (citable) accession number: A5GP97
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 12, 2007
Last modified: April 16, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries