A5GN69 (A5GN69_SYNPW) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase EMBL CAK24384.1
EC=3.5.1.- EMBL CAK24384.1

Gene names

Name:	lpxC EMBL CAK24384.1
Ordered Locus Names:	SynWH7803_1958

Organism

Synechococcus sp. (strain WH7803) [Complete proteome] [HAMAP]

Taxonomic identifier

32051 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	284 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS015870
Catalytic activity	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. SAAS SAAS015870
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. SAAS SAAS015870

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS015870 Lipid synthesis
Molecular function	Hydrolase SAAS SAAS015870 EMBL CAK24384.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A5GN69 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 99027CEB1415C54E	FASTA	284	30,654
	10 20 30 40 50 60 MVRWPVDYDG AWTLAGPVHR SGIGLHSGQP VSVTLKPSLE PGVWVQWASD DAAPVRLAPS 70 80 90 100 110 120 QVRDSQLCTT LDLGSRRLAT VEHLLAALAG CGLTHALLEV DGEEIPLLDG SALGWVEAIA 130 140 150 160 170 180 EADLLEVPGW HPQRPELEHP LALHRGSSVI TATPAEQFSV VGVIDFPQPA IGRQQFTLEL 190 200 210 220 230 240 TPQRFVEEIA PARTFGFRDQ VEHLRAAGLI QGGALDNALV CDGEHWLNPP LRFPDEPVRH 250 260 270 280 KLLDLIGDLA LVGFPRAQVL VYRGSHGLHA DLAAALADRS PVQP

References

[1]	Genoscope Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT971583 Genomic DNA. Translation: CAK24384.1.
RefSeq	YP_001225681.1. NC_009481.1.
3D structure databases
ProteinModelPortal	A5GN69.
ModBase	Search...
Protein-protein interaction databases
STRING	A5GN69.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5145925.
GenomeReviews	Gene locus SynWH7803_1958 in contig CT971583_GR.
KEGG	syx:SynWH7803_1958.
PATRIC	23830142. VBISynSp43824_2016.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0774.
HOGENOM	HBG482342.
OMA	KAYKSGH.
PhylomeDB	A5GN69.
ProtClustDB	PRK13186.
Enzyme and pathway databases
BioCyc	SSP32051:SYNWH7803_1958-MONOMER.
Family and domain databases
InterPro	IPR020568. Ribosomal_S5_D2-typ_fold. IPR004463. UDP-acyl_GlcNac_deAcase. IPR011334. UDP-acyl_GlcNac_deAcase_C. IPR015870. UDP-acyl_N-AcGlcN_deAcase_N. [Graphical view]
Gene3D	G3DSA:3.30.1700.10. UDP-acyl_N-AcGlcN_deAcase_C. 1 hit. G3DSA:3.30.230.20. UDP-acyl_N-AcGlcN_deAcase_N. 1 hit.
KO	K02535.
Pfam	PF03331. LpxC. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 2 hits.
TIGRFAMs	TIGR00325. LpxC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A5GN69_SYNPW

Accession

Primary (citable) accession number: A5GN69

Entry history

Integrated into UniProtKB/TrEMBL:	June 12, 2007
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)