A5GN68 (FABZ_SYNPW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
Short name=(3R)-hydroxymyristoyl ACP dehydrase
EC=4.2.1.-

Gene names

Name:	fabZ
Ordered Locus Names:	SynWH7803_1957

Organism

Synechococcus sp. (strain WH7803) [Complete proteome] [HAMAP]

Taxonomic identifier

32051 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	147 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in saturated fatty acids biosynthesis By similarity. HAMAP MF_00406
Subcellular location	Cytoplasm By similarity HAMAP MF_00406.
Sequence similarities	Belongs to the thioester dehydratase family. FabZ subfamily.

Ontologies

Keywords
Biological process	Lipid A biosynthesis Lipid synthesis
Cellular component	Cytoplasm
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: InterPro lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	hydro-lyase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 147	147	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase HAMAP MF_00406		PRO_0000340811
Sites
	Active site	53	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	A5GN68 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 6CB7A7C34D4652EA	FASTA	147	16,173
	10 20 30 40 50 60 MTSQPVLNAE QIMGLLPHRY PFALVDRVLE HVPGEKAVAI KNVTLNEPQF QGHFPDRPLM 70 80 90 100 110 120 PGVLIVEAMA QVGGLIVTQM PDLPKGLFVF AGIDGVRFRR PVVPGDQLRI SCELLSLKRQ 130 140 RFGKVKAEAT VEGQLVCSGE LMFSLVD

References

[1]	Genoscope Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: WH7803.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT971583 Genomic DNA. Translation: CAK24383.1.
RefSeq	YP_001225680.1. NC_009481.1.
3D structure databases
ProteinModelPortal	A5GN68.
ModBase	Search...
Protein-protein interaction databases
STRING	A5GN68.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5146103.
GenomeReviews	Gene locus SynWH7803_1957 in contig CT971583_GR.
KEGG	syx:SynWH7803_1957.
PATRIC	23830140. VBISynSp43824_2015.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0764.
HOGENOM	HBG433282.
OMA	KERRGVA.
PhylomeDB	A5GN68.
ProtClustDB	PRK00006.
Enzyme and pathway databases
BioCyc	SSP32051:SYNWH7803_1957-MONOMER.
Family and domain databases
HAMAP	MF_00406. FabZ. [Tree]
InterPro	IPR013114. FabA_FabZ. IPR010084. FabZ. [Graphical view]
KO	K02372.
Pfam	PF07977. FabA. 1 hit. [Graphical view]
TIGRFAMs	TIGR01750. FabZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FABZ_SYNPW

Accession

Primary (citable) accession number: A5GN68

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program