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Protein
Submitted name:

Ribosomal RNA small subunit methyltransferase B

Gene

rsmB

Organism
Synechococcus sp. (strain WH7803)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.SAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei296S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei323S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei344S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei397NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotationImported, RNA-bindingPROSITE-ProRule annotationSAAS annotation, Transferase
Biological processrRNA processingSAAS annotation
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Ribosomal RNA small subunit methyltransferase BImported (EC:2.1.1.-Imported)
Gene namesi
Name:rsmBImported
Ordered Locus Names:SynWH7803_1778Imported
OrganismiSynechococcus sp. (strain WH7803)Imported
Taxonomic identifieri32051 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesSynechococcaceaeSynechococcus
Proteomesi
  • UP000001566 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi32051.SynWH7803_1778.

Structurei

3D structure databases

ProteinModelPortaliA5GMN9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini181 – 447SAM_MT_RSMB_NOPInterPro annotationAdd BLAST267

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CYJ. Bacteria.
COG0144. LUCA.
HOGENOMiHOG000037300.
KOiK03500.
OMAiLRVNRQH.
OrthoDBiPOG091H02E2.

Family and domain databases

Gene3Di1.10.940.10. 1 hit.
InterProiView protein in InterPro
IPR018314. Fmu/NOL1/Nop2p_CS.
IPR001678. MeTrfase_RsmB/NOP2.
IPR006027. NusB_RsmB_TIM44.
IPR023267. RCMT.
IPR004573. rRNA_ssu_MeTfrase_B.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF01189. Methyltr_RsmB-F. 1 hit.
PF01029. NusB. 1 hit.
PRINTSiPR02008. RCMTFAMILY.
SUPFAMiSSF48013. SSF48013. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00563. rsmB. 1 hit.
PROSITEiView protein in PROSITE
PS01153. NOL1_NOP2_SUN. 1 hit.
PS51686. SAM_MT_RSMB_NOP. 1 hit.

Sequencei

Sequence statusi: Complete.

A5GMN9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSESPSRSET PGLASRRVAL EVLEAVAAGA YADVALERAL RQHPLQAADR
60 70 80 90 100
GLATELAYGA IRWRQWLDAW LDKLGKVPAR KQPPRLRWLL HLGLYQVLRM
110 120 130 140 150
ERIPAAAAVN TTVELAKRGK LARLAPVVNG LLRAALRARE AGDGLVQPTD
160 170 180 190 200
PALALAQNQS LPLWFTQDLL RWCGPAQAAQ VAQACNQVPP LDLRINRLRS
210 220 230 240 250
SPAEMAARLA ECSMPTAAIP GCPDGLQVLH SAGDLRQWPG YEEGHWCVQD
260 270 280 290 300
RAAQWVAPLL AVEPGQRVLD ACAAPGGKAT HLAELMGDQG EVWAVDRSGG
310 320 330 340 350
RLQRVAANAA RLGCGCINAL AADAAQLLEE RPQWRASFDR ILLDAPCSGL
360 370 380 390 400
GTLARHPDAR WRISEASIAD LVKLQAGLLD ALVPLLKPGG RIVYATCTVH
410 420 430 440
PAENTEQIHG WLQRHPQLVL ASEQQRWPDP QGGDGFYAAV ITAPAAA
Length:447
Mass (Da):48,208
Last modified:June 12, 2007 - v1
Checksum:i6160E9E202A1AF88
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT971583 Genomic DNA. Translation: CAK24204.1.
RefSeqiWP_011933676.1. NC_009481.1.

Genome annotation databases

EnsemblBacteriaiCAK24204; CAK24204; SynWH7803_1778.
KEGGisyx:SynWH7803_1778.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiA5GMN9_SYNPW
AccessioniPrimary (citable) accession number: A5GMN9
Entry historyiIntegrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: June 7, 2017
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported