A5GMN1 (SYGA_SYNPW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycine--tRNA ligase alpha subunit
EC=6.1.1.14

Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	SynWH7803_1770

Organism

Synechococcus sp. (strain WH7803) [Complete proteome] [HAMAP]

Taxonomic identifier

32051 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	296 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm HAMAP MF_00254.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glycine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 296	296	Glycine--tRNA ligase alpha subunit HAMAP MF_00254		PRO_1000047517

Sequences

	Sequence		Length	Mass (Da)
	A5GMN1 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: F2157E9959E1755C	FASTA	296	33,406
	10 20 30 40 50 60 MHFQDIISTL NRFWSEQGCL LLQPYDTEKG AGTMSPHTVL RAIGPEPWAV AYPEPCRRPT 70 80 90 100 110 120 DGRYGDNPNR AQHYFQYQVL IKPSPDGIQE TYLASLEALG IKAADHDIRF VEDNWESPTL 130 140 150 160 170 180 GAWGVGWEVW LDGMEVTQFT YFQQCGGLDC KPVSIEITYG LERLAMYLQD VESIWDLSWN 190 200 210 220 230 240 AQRSYGDIWL PFEKGQCHFN FEASNPERLK QLFAIYEAEA TDLIAQNLPA PALDFVLKCS 250 260 270 280 290 HTFNLLEARG VISVTERTAT IGRIRTLARK VAEAWLAERE ALGFPLLEPS AATAAV

References

[1]	Genoscope Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: WH7803.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT971583 Genomic DNA. Translation: CAK24196.1.
RefSeq	YP_001225493.1. NC_009481.1.
3D structure databases
ProteinModelPortal	A5GMN1.
SMR	A5GMN1. Positions 1-276.
ModBase	Search...
Protein-protein interaction databases
STRING	A5GMN1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5148444.
GenomeReviews	Gene locus SynWH7803_1770 in contig CT971583_GR.
KEGG	syx:SynWH7803_1770.
PATRIC	23829731. VBISynSp43824_1816.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0752.
HOGENOM	HBG285316.
OMA	CRRPTDG.
PhylomeDB	A5GMN1.
ProtClustDB	PRK09348.
Enzyme and pathway databases
BioCyc	SSP32051:SYNWH7803_1770-MONOMER.
Family and domain databases
HAMAP	MF_00254. Gly_tRNA_synth_alpha. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
KO	K01878.
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
TIGRFAMs	TIGR00388. GlyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_SYNPW

Accession

Primary (citable) accession number: A5GMN1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	June 12, 2007
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program