A5GMH4 (SURE_SYNPW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	SynWH7803_1713

Organism

Synechococcus sp. (strain WH7803) [Complete proteome] [HAMAP]

Taxonomic identifier

32051 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	269 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 269	269	5'-nucleotidase surE HAMAP MF_00060		PRO_0000335288
Sites
	Metal binding	11	1	Divalent metal cation By similarity
	Metal binding	12	1	Divalent metal cation By similarity
	Metal binding	43	1	Divalent metal cation By similarity
	Metal binding	101	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	A5GMH4 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: 7F0990DC3E7579D4	FASTA	269	28,977
	10 20 30 40 50 60 MAPLRILISN DDGVFADGIR ALAGAAAAAG HQVTVVCPDR ERSATGHGLT LQTPIRAEKA 70 80 90 100 110 120 DSLFDAGISA WACSGTPADC MKLALFELMD EAPDLVLSGI NHGPNLGTDV FCSGTVAAAM 130 140 150 160 170 180 EGTLEGLPSM AISSACFQWR DFQGAAALAV EVATAALRDQ WPENLLLNLN IPPCRPEVMG 190 200 210 220 230 240 PLRWTRLSIR RYDEQFSPRK DPRGRTYYWL AGEVVEDLES GGDGPRDWPT DVAQIEANSP 250 260 SLTPIQPELF WRGPLGGLPR LELNGQRVR

References

[1]	Genoscope Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: WH7803.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT971583 Genomic DNA. Translation: CAK24139.1.
RefSeq	YP_001225436.1. NC_009481.1.
3D structure databases
ProteinModelPortal	A5GMH4.
ModBase	Search...
Protein-protein interaction databases
STRING	A5GMH4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5146262.
GenomeReviews	Gene locus SynWH7803_1713 in contig CT971583_GR.
KEGG	syx:SynWH7803_1713.
PATRIC	23829603. VBISynSp43824_1756.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0496.
HOGENOM	HBG600532.
OMA	NGFYYVN.
PhylomeDB	A5GMH4.
ProtClustDB	PRK00346.
Enzyme and pathway databases
BioCyc	SSP32051:SYNWH7803_1713-MONOMER.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_SYNPW

Accession

Primary (citable) accession number: A5GMH4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program