Skip Header

 
Contribute Send feedback
Read comments (1) or add your own

Reviewed, UniProtKB/Swiss-Prot A5GKR3 (ACSF_SYNPW)

Last modified June 16, 2009. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Hide | Top

Names and origin

Protein namesRecommended name:
    Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase
      Short name=Mg-protoporphyrin IX monomethyl ester oxidative cyclase
    EC=1.14.13.81
Gene names
Name: acsF
Ordered Locus Names: SynWH7803_1102
OrganismSynechococcus sp. (strain WH7803) [Complete proteome] [HAMAP]
Taxonomic identifier32051 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Synechococcus

Hide | Top

Protein attributes

Sequence length360 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

Hide | Top

General annotation (Comments)

Function

Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) By similarity.

Catalytic activity

Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O. HAMAP MF_01840

131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O. HAMAP MF_01840

131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = divinylprotochlorophyllide + NADP+ + 2 H2O. HAMAP MF_01840

Cofactor

Iron By similarity.

Pathway

Porphyrin biosynthesis; chlorophyll biosynthesis (light-independent). HAMAP MF_01840

Sequence similarities

Belongs to the acsF family.

Hide | Top

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 360360Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase HAMAP MF_01840
PRO_1000070553

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
A5GKR3-1 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 66465D9F7D744B03

FASTA36041,422
        10         20         30         40         50         60 
MVPPTAVNDA PAAGSAVSVK DPAKDTILTP RFYTTDFEAM AAMDLRPNEA ELEAICEEFR 

        70         80         90        100        110        120 
KDYNRHHFVR NDEFEGAADK LDPETRRVFV EFLEQSCTSE FSGFLLYKEL SRRIKTRNPL 

       130        140        150        160        170        180 
LAECFAHMAR DEARHAGFLN KSMSDFGLQL DLGFLTANKS YTFFQPKFIF YATYLSEKIG 

       190        200        210        220        230        240 
YWRYITIFRH LEKNPDSKIF PIFNFFENWC QDENRHGDFF DALMKAQPNT VRGFRARLWC 

       250        260        270        280        290        300 
RFFLLAVFAT MYVRDVARKE FYEALGLDAR DYDRLVIDKT NETTARVFPV VLDVKNPKFY 

       310        320        330        340        350        360 
AGLENLVTNN AALDAVDASA SSAPIKVLRK LPHWIANGAQ MASLFLMAPV RSESFQPSVR

« Hide

Hide | Top

References

[1]Genoscope
Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Hide | Top

Cross-references

Sequence databases

CT971583 Genomic DNA. Translation: CAK23528.1.
RefSeqYP_001224825.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID5147809.
GenomeReviewsGene locus SynWH7803_1102 in contig CT971583_GR.
KEGGsyx:SynWH7803_1102.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAA5GKR3. SMSDFGL.

Family and domain databases

HAMAPMF_01840.
[Tree]
InterProIPR008434. AcsF.
IPR003251. Rubrerythrin.
[Graphical view]
PfamPF02915. Rubrerythrin. 1 hit.
[Graphical view]
TIGRFAMsTIGR02029. AcsF. 1 hit.
ProtoNetSearch...

Hide | Top

Entry information

Entry nameACSF_SYNPW
AccessionPrimary (citable) accession number: A5GKR3
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: June 12, 2007
Last modified: June 16, 2009
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Hide | Top

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents