A5GKJ5 (COMB_SYNPW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable 2-phosphosulfolactate phosphatase
EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	SynWH7803_1034

Organism

Synechococcus sp. (strain WH7803) [Complete proteome] [HAMAP]

Taxonomic identifier

32051 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	246 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity. HAMAP MF_00490
Sequence similarities	Belongs to the ComB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 246	246	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_1000014471

Sequences

	Sequence		Length	Mass (Da)
	A5GKJ5 [UniParc]. Last modified June 12, 2007. Version 1. Checksum: BCE80C2870BA3CC9	FASTA	246	26,525
	10 20 30 40 50 60 MQVSYFHVAA DVPDAIGSVE GPDAAVVIDV LRATTTIAWA LHNGAEAVQA FADLDELRLQ 70 80 90 100 110 120 SRNWPEQTRL LLGERGGRML EGFDLGNSPV AVIPEVVQGK RLFMSTTNGT RALQRVRDVS 130 140 150 160 170 180 VVMTVALPNR QAVAQRLLRD QPERVWMVGS GWEGTYSLED SLAAGALADA LVAAGAQVAN 190 200 210 220 230 240 DELQAALALW AQWKHDPEAC LRVASHGQRL TRLGNHDADF SCCAGLDQLS VVPTQTEPGV LRAIRV

References

[1]	Genoscope Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: WH7803.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT971583 Genomic DNA. Translation: CAK23460.1.
RefSeq	YP_001224757.1. NC_009481.1.
3D structure databases
ProteinModelPortal	A5GKJ5.
ModBase	Search...
Protein-protein interaction databases
STRING	A5GKJ5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5147839.
GenomeReviews	Gene locus SynWH7803_1034 in contig CT971583_GR.
KEGG	syx:SynWH7803_1034.
PATRIC	23828202. VBISynSp43824_1065.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2045.
HOGENOM	HBG633644.
OMA	GWEGAYS.
PhylomeDB	A5GKJ5.
ProtClustDB	PRK00886.
Family and domain databases
HAMAP	MF_00490. ComB. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. IPR022995. Pase_ComB. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
KO	K05979.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
SUPFAM	SSF142823. SSF142823. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_SYNPW

Accession

Primary (citable) accession number: A5GKJ5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	June 12, 2007
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program