Skip Header

Contribute Send feedback
Read comments (?) or add your own

A5GIP0 (EFTU_SYNPW) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Elongation factor Tu
Short name=EF-Tu
Gene names
Name:tuf
Ordered Locus Names:SynWH7803_0379
OrganismSynechococcus sp. (strain WH7803) [Complete proteome] [HAMAP]
Taxonomic identifier32051 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechococcus

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Molecular functionElongation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processGTP catabolic process

Inferred from electronic annotation. Source: GOC

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: HAMAP

GTPase activity

Inferred from electronic annotation. Source: InterPro

translation elongation factor activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 399399Elongation factor Tu HAMAP-Rule MF_00118
PRO_1000015770

Regions

Nucleotide binding19 – 268GTP By similarity
Nucleotide binding81 – 855GTP By similarity
Nucleotide binding136 – 1394GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
A5GIP0 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: B25A646C1FD7C22E

FASTA39943,674
        10         20         30         40         50         60 
MAREKFERNK PHVNIGTIGH VDHGKTTLTA AITNVLAKKG QAKVQDYADI DGAPEERERG 

        70         80         90        100        110        120 
ITINTAHVEY ETDTRHYAHV DCPGHADYVK NMITGAAQMD GAILVCAATD GPMAQTKEHI 

       130        140        150        160        170        180 
LLAKQVGVPA LVVALNKCDM VDDEEIIELV EMEIRELLSS YDFPGDDIPV VQVSGLKAIE 

       190        200        210        220        230        240 
GEAEWEAKID ELMQAVDANI PEPEREVDKP FLMAIEDVFS ITGRGTVATG RIERGIVKVG 

       250        260        270        280        290        300 
EEIEIVGIKD TRKTTVTGVE MFRKLLDEGM AGDNVGLLLR GIQKEDIERG MVLVKPGSIT 

       310        320        330        340        350        360 
PHTKFEGEVY VLKKEEGGRH TPFFAGYRPQ FYIRTTDVTG QITAFTADDG SDVEMVMPGD 

       370        380        390 
RIKMTGELIC PVAIEQGMRF AIREGGRTIG AGVVSKIIE

« Hide

References

[1]Genoscope
Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: WH7803.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CT971583 Genomic DNA. Translation: CAK22805.1.
RefSeqYP_001224102.1. NC_009481.1.

3D structure databases

ProteinModelPortalA5GIP0.
SMRA5GIP0. Positions 2-398.
ModBaseSearch...

Protein-protein interaction databases

STRING32051.SynWH7803_0379.

Proteomic databases

PRIDEA5GIP0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAK22805; CAK22805; SynWH7803_0379.
GeneID5146494.
KEGGsyx:SynWH7803_0379.
PATRIC23826812. VBISynSp43824_0385.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0050.
HOGENOMHOG000229290.
KOK02358.
OMASNVEMVM.
ProtClustDBPRK00049.

Family and domain databases

HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR005225. Small_GTP-bd_dom.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
IPR009000. Transl_elong_init/rib_B-barrel.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50465. Elong_init_C. 1 hit.
SSF50447. Translat_factor. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEFTU_SYNPW
AccessionPrimary (citable) accession number: A5GIP0
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 12, 2007
Last modified: May 1, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents