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A5GI65 (A5GI65_SYNPW) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonuclease 3 HAMAP-Rule MF_00104
EC=3.1.26.3 HAMAP-Rule MF_00104
Alternative name(s):
Ribonuclease III HAMAP-Rule MF_00104
Gene names
Name:rnc HAMAP-Rule MF_00104 EMBL CAK22630.1
Ordered Locus Names:SynWH7803_0204
OrganismSynechococcus sp. (strain WH7803) [Complete proteome] [HAMAP]
Taxonomic identifier32051 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechococcus

Protein attributes

Sequence length240 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon By similarity. HAMAP-Rule MF_00104

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP-Rule MF_00104 SAAS SAAS011907

Cofactor

Mg2+ By similarity. HAMAP-Rule MF_00104 SAAS SAAS000999

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00104 SAAS SAAS011907

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00104 SAAS SAAS011907.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain. HAMAP-Rule MF_00104 SAAS SAAS011907

Contains 1 RNase III domain. HAMAP-Rule MF_00104 SAAS SAAS011907

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain10 – 137128RNase III By similarity HAMAP-Rule MF_00104
Domain164 – 23471DRBM By similarity HAMAP-Rule MF_00104

Sites

Active site551 By similarity HAMAP-Rule MF_00104
Metal binding511Magnesium By similarity HAMAP-Rule MF_00104
Metal binding1231Magnesium By similarity HAMAP-Rule MF_00104
Metal binding1261Magnesium By similarity HAMAP-Rule MF_00104

Sequences

Sequence LengthMass (Da)Tools
A5GI65 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: 3C3A9C099B4E4679

FASTA24026,196
        10         20         30         40         50         60 
MQEANRDQQL RLLWIELGNN PERLQRAEFD CLNEALTHTS SGLNPHHEQL EFLGDAVLRL 

        70         80         90        100        110        120 
AASEFIATAY PQMPVGERSS LRAQLVSDRW LAQLGEAIAI AQWWRIGPKA SGDPSAAATI 

       130        140        150        160        170        180 
RAELSEALIG AVYRIAGLQT VQAWLTPHWQ TSAEAVLADP YRGNSKSALQ EWSQGQGLGL 

       190        200        210        220        230        240 
PRYSCSEVSQ SHGDPKRFQA SVTLPPDLSA AGWGGSRREA EQQAAEALMA QLKASSTDRA

« Hide

References

[1]Genoscope
Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: WH7803.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CT971583 Genomic DNA. Translation: CAK22630.1.
RefSeqYP_001223927.1. NC_009481.1.

3D structure databases

ProteinModelPortalA5GI65.
ModBaseSearch...

Protein-protein interaction databases

STRING32051.SynWH7803_0204.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAK22630; CAK22630; SynWH7803_0204.
GeneID5146706.
KEGGsyx:SynWH7803_0204.
PATRIC23826448. VBISynSp43824_0208.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0571.
HOGENOMHOG000246808.
KOK03685.
OMAALQEWTQ.
ProtClustDBCLSK848172.

Family and domain databases

Gene3D1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPMF_00104. RNase_III.
InterProIPR001159. Ds-RNA-bd.
IPR014720. dsRNA-bd-like_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF00636. Ribonuclease_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. RNase_III. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA5GI65_SYNPW
AccessionPrimary (citable) accession number: A5GI65
Entry history
Integrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: May 1, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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