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A5GF03 (AROC_GEOUR) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:Gura_1818
OrganismGeobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens) [Complete proteome] [HAMAP]
Taxonomic identifier351605 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Geobacteraceae › Geobacter

Protein attributes

Sequence length393 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 393393Chorismate synthase HAMAP MF_00300
PRO_1000078995

Sequences

Sequence LengthMass (Da)Tools
A5GF03 [UniParc].

Last modified June 12, 2007. Version 1.
Checksum: A2C07863DE0872B0

FASTA39342,994
        10         20         30         40         50         60 
MFRYLTAGES HGPQLTAIIE GIPAGLSLSE EQINIDLARR QCGYGRGGRM LIEKDQVEIL 

        70         80         90        100        110        120 
SGVRWGKTIG SPITLCVRNR DWENWHEKMS PHERFHDDKI RVTRSRPGHA DLPGAMKYNH 

       130        140        150        160        170        180 
HDVRNILERS SARETAVRVA VGAVAKALLS QFEIEVCGFV AELGGIKAIR PSLPLAALKD 

       190        200        210        220        230        240 
MAAKSELFTY DKSVEEEMKR LIDTVRDEGD TVGGVIEVNA VGVPPGLGSH VQWDRKLDAR 

       250        260        270        280        290        300 
LAMAVLSIQA FKGVEIGIGF QAAASTGSKV HDEIFYDSAR IAHGEQSGFY RKSNNAGGIE 

       310        320        330        340        350        360 
GGISNGEEIV VRAAMKPIPT LYKPLRSVDI VSKEPYEATV ERSDVCAVPA ASVVAEAVVA 

       370        380        390 
IELADAFMVK FGGDSITEIK RNYQSYLDYL RAF

« Hide

References

[1]"Complete sequence of Geobacter uraniireducens Rf4."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Mikhailova N., Shelobolina E., Aklujkar M., Lovley D., Richardson P.
Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Rf4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000698 Genomic DNA. Translation: ABQ26008.1.
RefSeqYP_001230581.1. NC_009483.1.

3D structure databases

ProteinModelPortalA5GF03.
SMRA5GF03. Positions 2-393.
ModBaseSearch...

Protein-protein interaction databases

STRINGA5GF03.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5163977.
GenomeReviewsGene locus Gura_1818 in contig CP000698_GR.
KEGGgur:Gura_1818.
NMPDRfig|351605.3.peg.3152.
PATRIC22033732. VBIGeoUra13052_1947.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0082.
HOGENOMHBG292336.
OMAMLRWLTA.
ProtClustDBPRK05382.

Enzyme and pathway databases

BioCycGURA351605:GURA_1818-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_GEOUR
AccessionPrimary (citable) accession number: A5GF03
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: June 12, 2007
Last modified: January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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